{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T01:01:03Z","timestamp":1762909263437,"version":"3.45.0"},"reference-count":43,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T00:00:00Z","timestamp":1750896000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aocs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lipids"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Fatty acid (FA) metabolism is associated with Demodicosis, an increasingly common skin condition frequently observed in adolescents and adults, but it is not yet well defined whether the distribution or location of FAs in facial sebum differs according to the disease. In a study with a group of 50 patients diagnosed with Demodicosis and 40 control subjects, sebum samples were collected from the forehead, cheeks, and chin areas using Sebutape patches. Total FAs were analyzed using gas chromatography. The patients with Demodex were divided into two groups. Twenty\u2010five individuals used only the placebo cosmetic base, while the other 25 applied the target product. The extraction of key active ingredients aligns with the trend of sustainable cosmetic production and upcycling. Compared to healthy women, the female patients showed higher levels of saturated fatty acids (SFAs) and monounsaturated fatty acids (MUFAs) from both facial areas, while lower levels of polyunsaturated fatty acids (PUFAs) were observed in the chin area samples. Patients with Demodicosis exhibited more pronounced abnormalities in sebum and specific FA profiles in the chin area, consistent with the higher incidence of Demodicosis in adult women, particularly in these facial areas. The differential distribution of FAs in facial sebum and its correlation with the occurrence of Demodicosis led to the application of innovative upcycling ingredients. The purpose of the experiment was to determine the difference in the FA profile between individuals with and without Demodicosis.<\/jats:p>","DOI":"10.1002\/lipd.12454","type":"journal-article","created":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T23:18:43Z","timestamp":1750979923000},"page":"423-433","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Effect of a Preparation Derived From Fish Skin on the Change in the Fatty Acid Composition of Sebum in Individuals With Demodicosis"],"prefix":"10.1002","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7017-7392","authenticated-orcid":false,"given":"Joanna","family":"Igielska\u2010Kalwat","sequence":"first","affiliation":[{"name":"Faculty of Food Science and Nutrition Pozna\u0144 University of LifeSciences  Poznan Poland"},{"name":"Faculty of Cosmetology University of Education and Therapy  Poznan Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewa","family":"Kilian\u2010Pi\u0119ta","sequence":"additional","affiliation":[{"name":"Laboratory Symbiosis  Poznan Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maciej","family":"Siedlecki","sequence":"additional","affiliation":[{"name":"Faculty of Civil Engineering and Transport Institute of Combustion Engines and Powertains  Poznan Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2014.192"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346\u20108138.12659"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.02.634"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610\u20100387.2005.05725.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/cosmetics2020082"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2010.22.2.125"},{"key":"e_1_2_10_8_1","first-page":"51","article-title":"Demodex in the Etiopathogenesis of Certain Skin Diseases","volume":"18","author":"Bohdanowicz D.","year":"2001","journal-title":"Postepy Dermatologii I Alergologii"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.06.045"},{"key":"e_1_2_10_10_1","first-page":"145","article-title":"Molecular Background of Pigmentation Disorders in Skin Diseases","volume":"66","author":"Druka\u0142a J.","year":"2009","journal-title":"Przegla\u0105d Lekarski"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1039\/d1gc03081g"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2327"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.23880\/CDOAJ-16000257"},{"issue":"1","key":"e_1_2_10_14_1","first-page":"1","article-title":"The Use of Natural Collagen Obtained From Fish Waste in Eye Laminate Care","volume":"6","author":"Igielska\u2010Kalwat J.","year":"2024","journal-title":"Dermatological Research"},{"issue":"1","key":"e_1_2_10_15_1","first-page":"1","article-title":"In Vivo Studies of Cosmetics With a Filter and Synergistic Antioxidant Care","volume":"5","author":"Igielska\u2010Kalwat J.","year":"2024","journal-title":"Journal of Dermatological Research"},{"key":"e_1_2_10_16_1","first-page":"40675","article-title":"Antibacterial, Antiparasitic and Antifungal Properties of Natural Pyrethrins Obtained From Dalmatian Tansy Used in the Treatment and Care of Sensitive Skin","volume":"49","author":"Igielska\u2010Kalwat J.","year":"2023","journal-title":"Journal of Science and Technological Researches"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/polym14040749"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.23880\/cdoaj\u201016000297"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/ics.13015"},{"issue":"2","key":"e_1_2_10_20_1","first-page":"1","article-title":"The Use of Natural Collagen Obtained From Fish Waste in Hair Care","volume":"5","author":"Igielska\u2010Kalwat J.","year":"2024","journal-title":"Journal of Dermatological Research"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.18388\/abp.2020_5770"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2008.06.004"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102133.2009.09337.x"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2000.107414"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32023"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1398\u20109995.2003.00032.x"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/app.1993.070501114"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100625.2009.00809.x"},{"issue":"4","key":"e_1_2_10_29_1","first-page":"114","article-title":"Atopic Dermatitis \u2013 Pathomechanism, Diagnosis, Therapeutic Management, Prevention","volume":"21","author":"Millan M.","year":"2017","journal-title":"Nowa Pediatria"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cherd.2016.03.014"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523\u20101747.ep12454833"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1767"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1159\/000029939"},{"key":"e_1_2_10_34_1","article-title":"Electrical conductivity of fish skin collagen in the temperature range 290\u2013380 K","volume":"2002","author":"Przybylski J. E.","year":"2002","journal-title":"Patent"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610\u20100387.2010.07498.x"},{"issue":"3","key":"e_1_2_10_36_1","first-page":"144","article-title":"Ocular Rosacea \u2013 Current Etiopathogenetic, Clinical, and Therapeutic Data, and Description of Three Cases","volume":"21","author":"Raszeja\u2010Kotelba B.","year":"2004","journal-title":"Postepy Dermatologii I Alergologii"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.2340\/actadv.v101.569"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.3390\/cleantechnol6010011"},{"issue":"7","key":"e_1_2_10_39_1","first-page":"120","article-title":"Cosmetics for the Care of Atopic Skin","volume":"65","author":"\u015aliwa K.","year":"2011","journal-title":"Wiadomo\u015bci Chemiczne"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph5080837"},{"key":"e_1_2_10_41_1","first-page":"47","article-title":"Atopic Dermatitis \u2013 The First Clinical Manifestation of Allergic Disease","volume":"11","author":"Wanat\u2010Krzak M.","year":"2004","journal-title":"Terapia"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2011.09.034"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2005.10.012"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1177\/20406223221149513"}],"container-title":["Lipids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aocs.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lipd.12454","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:57:15Z","timestamp":1762909035000},"score":1,"resource":{"primary":{"URL":"https:\/\/aocs.onlinelibrary.wiley.com\/doi\/10.1002\/lipd.12454"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,26]]},"references-count":43,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1002\/lipd.12454"],"URL":"https:\/\/doi.org\/10.1002\/lipd.12454","archive":["Portico"],"relation":{},"ISSN":["0024-4201","1558-9307"],"issn-type":[{"type":"print","value":"0024-4201"},{"type":"electronic","value":"1558-9307"}],"subject":[],"published":{"date-parts":[[2025,6,26]]},"assertion":[{"value":"2025-03-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}