{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T09:59:43Z","timestamp":1753869583768,"version":"3.41.2"},"reference-count":43,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,9,14]],"date-time":"2024-09-14T00:00:00Z","timestamp":1726272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Learning Health Systems"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Medication adherence data are an important quality indicator in cystic fibrosis (CF) care, yet real\u2010time objective data are not routinely available. An online application (CFHealthHub) has been designed to deliver these data to people with CF and their clinical team. Adoption of this innovation is the focus of an National Health Service England\u2010funded learning health system and Quality Improvement Collaborative (QIC). This study applies the capability, opportunity, and motivation model of behavior change to assess whether the QIC had supported healthcare professionals' uptake of accessing patient adherence data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This was a mixed\u2010method study, treating each multidisciplinary team as an individual case. Click analytic data from CFHealthHub were collected between January 1, 2018, and September 22, 2019. Thirteen healthcare practitioners participated in semi\u2010structured interviews, before and after establishing the QIC. Qualitative data were analyzed using the behavior change model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The cases showed varied improvement trajectories. While two cases reported reduced barriers, one faced persistent challenges. Participation in the QIC led to enhanced confidence in the platform's utility. Reduced capability, opportunity, and motivation barriers correlated with increased uptake, demonstrating value in integrating behavior change theory into QICs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>QICs can successfully reduce barriers and enable uptake of e\u2010health innovations such as adherence monitoring technology. However, ongoing multi\u2010level strategies are needed to embed changes. Further research should explore sustainability mechanisms and their impact on patient outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lrh2.10453","type":"journal-article","created":{"date-parts":[[2024,9,14]],"date-time":"2024-09-14T08:33:27Z","timestamp":1726302807000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Changing practice in cystic fibrosis: Implementing objective medication adherence data at every consultation, a learning health system and quality improvement collaborative"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4216-214X","authenticated-orcid":false,"given":"Carla","family":"Girling","sequence":"first","affiliation":[{"name":"Clinical Trials Research Unit University of Sheffield  Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4900-7695","authenticated-orcid":false,"given":"India","family":"Davids","sequence":"additional","affiliation":[{"name":"Clinical Trials Research Unit University of Sheffield  Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikki","family":"Totton","sequence":"additional","affiliation":[{"name":"Clinical Trials Research Unit University of Sheffield  Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madelynne A.","family":"Arden","sequence":"additional","affiliation":[{"name":"Department of Psychology, Sociology and Politics Sheffield Hallam University  Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Hind","sequence":"additional","affiliation":[{"name":"Clinical Trials Research Unit University of Sheffield  Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin J.","family":"Wildman","sequence":"additional","affiliation":[{"name":"Sheffield Adult Cystic Fibrosis Unit Sheffield Teaching Hospitals NHS Foundation Trust Northern General Hospital  Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,9,14]]},"reference":[{"unstructured":"CharmanS McClenaghanE CosgriffR LeeA CarrS.UK Cystic Fibrosis Registry Annual data report 2018.2019. 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