{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T08:06:01Z","timestamp":1784880361154,"version":"3.55.0"},"reference-count":44,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T00:00:00Z","timestamp":1764806400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T00:00:00Z","timestamp":1764806400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Learning Health Systems"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Germline testing and pretest genetic counseling are advised for many cancer patients, yet not all receive these services. Electronic Health Records (EHRs) offer a valuable resource to measure referral to genetic counseling (referral receipt) and uptake (completion of counseling). This study uses EHR data to assess demographic factors influencing genetic counseling referral and uptake among prostate cancer patients, serving as a learning health system model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We included prostate cancer patients who met germline testing and counseling criteria at an NCI\u2010designated cancer center from January 1, 2018, to June 30, 2022. Demographic factors\u2014age at diagnosis, race, employment, insurance, and geographic region\u2014were assessed for associations with genetic counseling referral and uptake. Analyses involved descriptive statistics, two\u2010group comparisons, and regression models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 356 prostate cancer patients, only 34.2% received genetic counseling referrals, and of these, 73% completed a counseling visit. Older patients were less likely to receive referrals (OR\u2009=\u20090.93, 95% CI [0.89\u20130.97]) and complete visits (OR\u2009=\u20090.92, 95% CI [0.87\u20130.96]). Patients employed full\u2010time were more likely to receive referrals (39.2% vs. 23.1%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01), while White (93% vs. 81%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.047) and rural patients (42.7% vs. 6.1%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02) had higher uptake. Insurance status did not significantly affect referral or uptake.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study demonstrates the potential of EHRs to identify demographic disparities in genetic counseling services. Using a learning health system approach, healthcare institutions can leverage EHR data to design targeted interventions aimed at improving access and reducing disparities in genetic services, ultimately enhancing patient outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lrh2.70049","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T07:40:53Z","timestamp":1764920453000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Exploring Factors That Impact Genetic Counseling Referral and Uptake Using Learning Health Approaches"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4994-4793","authenticated-orcid":false,"given":"Samantha","family":"Greenberg","sequence":"first","affiliation":[{"name":"Department of Health Care Sciences UT Southwestern Medical Center  Dallas Texas USA"},{"name":"College of Nursing University of Utah  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bob","family":"Wong","sequence":"additional","affiliation":[{"name":"College of Nursing University of Utah  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine A.","family":"Sward","sequence":"additional","affiliation":[{"name":"College of Nursing University of Utah  Salt Lake City Utah USA"},{"name":"Department of Biomedical Informatics, Spencer Fox Eccles School of Medicine University of Utah  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen A.","family":"Cooney","sequence":"additional","affiliation":[{"name":"Department of Medicine Duke University School of Medicine  Durham North Carolina USA"},{"name":"Duke Cancer Institute Duke University  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Tward","sequence":"additional","affiliation":[{"name":"Huntsman Cancer Institute University of Utah  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Post","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, Spencer Fox Eccles School of Medicine University of Utah  Salt Lake City Utah USA"},{"name":"Huntsman Cancer Institute University of Utah  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mollie R.","family":"Cummins","sequence":"additional","affiliation":[{"name":"College of Nursing University of Utah  Salt Lake City Utah USA"},{"name":"Department of Biomedical Informatics, Spencer Fox Eccles School of Medicine University of Utah  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,4]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.23.02225"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.63.0996"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urolonc.2020.10.014"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2019.01.024"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2023.41.16_suppl.10549"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/cge.14100"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2019.7984"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2019.06.012"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/tbj.13440"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2018.04.004"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1158\/1538-7755.DISP23-A066"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctarc.2022.100588"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.4684"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.00642"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2017.122"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACM.0000000000004712"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/lrh2.10315"},{"key":"e_1_2_10_19_1","unstructured":"M. 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