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Persistence or absence of disease was evaluated with respect to severity of disease, size of lesion, method of applying laser, whether the endocervical canal was involved, whether only the lesion or the entire transformation zone was lasered, and depth of laser effect. The persistence of disease was 36.7 percent after therapy. Success was not related to severity of disease, size of lesion, or whether the endocervical canal was involved. It was related to depth of coagulation necrosis, method of applying the laser beam, and if the entire transformation zone was treated.<\/jats:p>","DOI":"10.1002\/lsm.1900010202","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T00:31:53Z","timestamp":1172881913000},"page":"113-122","source":"Crossref","is-referenced-by-count":23,"title":["Carbon dioxide laser therapy of cervical intraepithelial neoplasia: Factors determining success rate"],"prefix":"10.1002","volume":"1","author":[{"given":"Louis","family":"Burke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Covell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald","family":"Antonioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,12,12]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"371","article-title":"Carbon dioxide laser in gynecology","volume":"6","author":"Bellina JH","year":"1977","journal-title":"Obstet Gynecol Annu"},{"key":"e_1_2_1_3_2","first-page":"72","article-title":"Gynecologic surgery using the CO2 laser","volume":"63","author":"Adducci JE","year":"1978","journal-title":"Int Surg"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(76)90629-3"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197804)41:4<1405::AID-CNCR2820410427>3.0.CO;2-S"},{"key":"e_1_2_1_6_2","first-page":"301","volume-title":"Pathology Annual","author":"Richart RM","year":"1973"},{"key":"e_1_2_1_7_2","first-page":"133","volume-title":"Colposcopy","author":"Coppleson M","year":"1971"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(68)90188-9"},{"key":"e_1_2_1_9_2","first-page":"196","article-title":"Electrocoagulation, diathermy for the treatment of cervical dysplasia and carcinoma\u2010in\u2010situ","volume":"47","author":"Hollyock VE","year":"1976","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(71)90660-0"},{"key":"e_1_2_1_11_2","first-page":"501","article-title":"Efficacy of cryosurgical treatment of severe cervical intraepithelial neoplasia","volume":"41","author":"Creasman WJ","year":"1973","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-197901010-00027"},{"key":"e_1_2_1_13_2","first-page":"171","article-title":"Cryocauterization for pre\u2010invasive cervical neoplasia","volume":"6","author":"Townsend DE","year":"1971","journal-title":"J Reprod Med"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(73)90104-X"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(77)90676-7"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.1900010202","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.1900010202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T04:12:09Z","timestamp":1699848729000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.1900010202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,1]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1980,1]]}},"alternative-id":["10.1002\/lsm.1900010202"],"URL":"https:\/\/doi.org\/10.1002\/lsm.1900010202","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,1]]}}}