{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T21:57:29Z","timestamp":1757541449680},"reference-count":6,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,12,12]],"date-time":"2005-12-12T00:00:00Z","timestamp":1134345600000},"content-version":"vor","delay-in-days":8381,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[1983,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>For studying microcirculation of intact tissues or organs, a new noninvasive, heat\u2010transient method using laser photoexcitation is described. As a heating source an argon ion laser or R6G dye laser was used via a quartz fiber optic guide. Infrared radiation from heated tissue was detected by a thermography apparatus. After switching the laser irradiation on and off, a thermal transient curve of a model tissue, the skin, was biphasic: a component with a fast time constant and the other with a slow time constant. The temperature increases of both phases following laser irradiation were linear to the applied power from the laser onto the tissue. The temperature rises as a function of the wavelength of irradiated light have shown that the absorption of the light by tissue hemoglobin is a main heat\u2010generation source. Furthermore, the temperature rises as a function of tissue blood volume and flow have shown that the component with a slow time constant is more related to the tissue hemoglobin concentration and tissue blood flow and heat conductivity. Thus, the analysis of heat\u2010transient curves following laser irradiation gives information as to regional tissue blood volume, blood flow, and tissue heat conductivity.<\/jats:p>","DOI":"10.1002\/lsm.1900020311","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T05:51:55Z","timestamp":1172901115000},"page":"275-280","source":"Crossref","is-referenced-by-count":2,"title":["Noninvasive assessment of microcirculation of living organs and tissues using laser"],"prefix":"10.1002","volume":"2","author":[{"given":"Takenobu","family":"Kamada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuhiro","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naomichi","family":"Kakubari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyoshi","family":"Yoda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunao","family":"Kawano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motoaki","family":"Schichiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Abe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196701262760407"},{"key":"e_1_2_1_3_2","first-page":"1507","volume-title":"Frontiers in Bioenergetics","author":"Sato N","year":"1978"},{"key":"e_1_2_1_4_2","first-page":"319","volume-title":"Cytochrome Oxidase.","author":"Sato N","year":"1979"},{"key":"e_1_2_1_5_2","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/S0016-5085(79)80183-3","article-title":"Measurement of hemoperfusion and oxygen sufficiency in gastric mucosa in vivo","volume":"76","author":"Sato N","year":"1979","journal-title":"Gastroenterology"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4757-1419-7_35"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2728(81)90122-5"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.1900020311","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.1900020311","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T18:53:23Z","timestamp":1697741603000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.1900020311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,1]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1983,1]]}},"alternative-id":["10.1002\/lsm.1900020311"],"URL":"https:\/\/doi.org\/10.1002\/lsm.1900020311","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,1]]}}}