{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T17:48:35Z","timestamp":1757699315482},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,10,19]],"date-time":"2005-10-19T00:00:00Z","timestamp":1129680000000},"content-version":"vor","delay-in-days":7231,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[1986,1]]},"abstract":"Abstract<\/jats:title>During the past 6 years, we have managed 633 cervical intraepithelial neoplasias with the Co2<\/jats:sub> laser. If the lesion is located on the ectocervix, the CO2<\/jats:sub> laser is used to vaporize it under the microscope. If the lesion is located in the endocervical canal, the CO2<\/jats:sub> laser is used to excise a cylinder\u2010shaped tissue with a handpiece.<\/jats:p>Colposcopic examination is performed 21 days after treatment. Persistent disease is recognized at this examination; healing is obtained spontaneously in 66% of those with persistent disease without second treatment.<\/jats:p>There were eight with recurrent disease with abnormal Pap tests and abnormal colposcopic findings, and 12 with recurrent disease with abnormal Pap tests and normal colposcopic findings (recurrent koilocytis cells).<\/jats:p>After laser treatment cervical function was good and pregnancies were normal.<\/jats:p>","DOI":"10.1002\/lsm.1900060204","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T09:29:49Z","timestamp":1172914189000},"page":"110-118","source":"Crossref","is-referenced-by-count":9,"title":["Management of 633 cervical intraepithelial neoplasias by CO2<\/sub> laser: Persistent diseases and recurrences"],"prefix":"10.1002","volume":"6","author":[{"given":"George D.","family":"Sadoul","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Th\u00e9r\u00e8se M.","family":"Beuret","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,10,19]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"720","article-title":"Treatment of cervical intraepithelial neoplasia with the carbon dioxide laser: Report of 543 patients","volume":"59","author":"Anderson MC","year":"1982","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_3_1","first-page":"378","article-title":"Mangement of cervical intraepithelial neoplasia by carbon dioxide laser","volume":"60","author":"Baggish MS","year":"1982","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(81)90712-2"},{"key":"e_1_2_1_5_1","first-page":"673","article-title":"The results of treatment of 4,839 cases of preclincial cervical squamous carcinoma","volume":"80","author":"Boyes DA","journal-title":"J Obstet Gynecol Br Common"},{"key":"e_1_2_1_6_1","first-page":"539","article-title":"Treatment of carcinoma in situ: Evaluation of 1,609 cases","volume":"55","author":"Burghardt E","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_7_1","first-page":"205","volume-title":"Fundamental Principles and Clincial Practice","author":"Coppleson M","year":"1981"},{"key":"e_1_2_1_8_1","first-page":"565","article-title":"Microsurgical conization of the cervix by carbon dioxide laser","volume":"54","author":"Dorsey JH","year":"1979","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1984.tb05906.x"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-197911000-00016"},{"key":"e_1_2_1_11_1","first-page":"125","article-title":"Long term follow\u2010up of 1,121 cases of carcinoma in situ","volume":"48","author":"Kolstad P","year":"1976","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_12_1","first-page":"1561","article-title":"Zur technique der konization","volume":"90","author":"Krauss A","year":"1968","journal-title":"Zentralbl Gynakol"},{"key":"e_1_2_1_13_1","first-page":"379","article-title":"Condylomatous lesions of the cervix II. Cytology, colposcopic and histotogic study","volume":"21","author":"Meisels A","year":"1977","journal-title":"Acta Cytol"},{"key":"e_1_2_1_14_1","first-page":"26","article-title":"Cytology of gynecologic condyloma acuminatum","volume":"21","author":"Purola E","year":"1977","journal-title":"Acta Cytol"},{"key":"e_1_2_1_15_1","first-page":"93","volume":"22","author":"Sturmdorf A","year":"1916","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_1_16_1","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0002-9378(83)90487-8","article-title":"Laser surgery for cervical intraepithelial neoplasia: Principles and results","volume":"45","author":"Wright VC","year":"1983","journal-title":"Am J Obstet Gynecol"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.1900060204","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.1900060204","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T09:35:28Z","timestamp":1697880928000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.1900060204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,1]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1986,1]]}},"alternative-id":["10.1002\/lsm.1900060204"],"URL":"https:\/\/doi.org\/10.1002\/lsm.1900060204","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,1]]}}}