{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T18:21:08Z","timestamp":1759602068953},"reference-count":12,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,10,19]],"date-time":"2005-10-19T00:00:00Z","timestamp":1129680000000},"content-version":"vor","delay-in-days":5770,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[1990,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Seven patients with malignant liver tumors were treated with Nd:YAG laser induced hyperthermia. The laserthermia was performed during laparotomy using Nd:YAG laser with contact sapphire probes with power settings of 6 W. The contact tip was placed into the middle of the tumor and the temperature in 1.5\u20102.0cm from the middle of the tumor was raised and held between 41C and 45C for ten minutes. One fatal complication appeared caused by an air embolism. In the postoperative fine needle biopsies on third and fifth postoperative day the sytologic finding in the tumor was necrosis. However, in 30% of the samples there was also a suspicion of cancer cells. In the computer tomography four weeks after the treatment there were also signs of necrosis. It seems that selective destruction of malignant liver tumors is possible with contact Nd:YAG laser induced hyperthemia.<\/jats:p>","DOI":"10.1002\/lsm.1900100403","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T13:19:42Z","timestamp":1172927982000},"page":"319-321","source":"Crossref","is-referenced-by-count":53,"title":["Laser\u2010Induced hyperthermia in the treatment of liver tumors"],"prefix":"10.1002","volume":"10","author":[{"given":"Juha","family":"Hahl","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reijo","family":"Haapiainen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jari","family":"Ovaska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pauli","family":"Puolakkainen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom","family":"Schr\u00f6der","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,10,19]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1912.04270120132016"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1927.tb00237.x"},{"key":"e_1_2_1_4_2","first-page":"4878","article-title":"The role of whole body hyperthermia in the treatment of neoplastic disease, its current status and future prospects","volume":"44","author":"Robins HI","year":"1984","journal-title":"Cancer Res"},{"key":"e_1_2_1_5_2","first-page":"679","article-title":"Clinical effects of whole body hyperthermia in advanced malignancy","volume":"4","author":"Pettigrew RT","year":"1974","journal-title":"Br J Surg"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19841201)54:2 <2823::AID-CNCR2820541430>3.0.CO;2-7"},{"key":"e_1_2_1_7_2","first-page":"35","article-title":"Interstitial thermoradiography: An overview","volume":"1","author":"Emami B","year":"1985","journal-title":"Endocurietherapy\/Hypothermia Oncol"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197712)40:6<2854::AID-CNCR2820400616>3.0.CO;2-L"},{"key":"e_1_2_1_9_2","first-page":"108","article-title":"Temperature distributions in tissues during local hyperthermia by stationary or steered beams of unfocused and focused ultrasound","volume":"45","author":"Lele PP","year":"1982","journal-title":"Br J Cancer [Suppl]"},{"key":"e_1_2_1_10_2","first-page":"275","article-title":"Laserthermia: A computer controlled contact Nd:YAG system for interstitial local hyperthermia","volume":"21","author":"Diakuzono N","year":"1987","journal-title":"Med Instrum"},{"key":"e_1_2_1_11_2","first-page":"59","volume-title":"Neodymium\u2010YAG Laser in Medicine and Surgery","author":"Bown SG","year":"1983"},{"key":"e_1_2_1_12_2","first-page":"161","article-title":"Experimental studies of local hyperthermia using Nd:YAG laser","volume":"17","author":"Tajiri H","year":"1986","journal-title":"Oncologia"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900090215"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.1900100403","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.1900100403","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T20:32:39Z","timestamp":1698006759000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.1900100403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,1]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1990,1]]}},"alternative-id":["10.1002\/lsm.1900100403"],"URL":"https:\/\/doi.org\/10.1002\/lsm.1900100403","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,1]]}}}