{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T02:20:44Z","timestamp":1700187644210},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,10,19]],"date-time":"2005-10-19T00:00:00Z","timestamp":1129680000000},"content-version":"vor","delay-in-days":5770,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[1990,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In the past, interstitial laser therapy frequently has failed because of the damage to the bare fiber tip due to intense heat generated at the point of contact. Using a rat mammary tumor model, we describe a method of placing a 600 micron fiber inside a gauge 19 needle cannula after its insertion into the tumor. With this device continuous wave Nd:YAG laser is delivered to the target tumor while 0.9% saline flows para\u2010axially into the tumor. Significant coagulation necrosis was induced with 500 joules at 5 watts, 100 seconds and 1 cc per minute of saline while the needle\u2010fiber is pulled out of the tumor by 10 mm. The mean transmission loss after 500 joules was 2% in ten experiments. The tumor edema due to 1.5 ml of saline was transient. We conclude that successful hyperthermic coagulation necrosis by Nd:YAG laser can be achieved with minimal transmission loss by employing the above technique.<\/jats:p>","DOI":"10.1002\/lsm.1900100404","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T13:19:42Z","timestamp":1172927982000},"page":"322-327","source":"Crossref","is-referenced-by-count":20,"title":["Protection of fiber function by para\u2010Axial fluid flow in interstitial laser therapy of malignant tumors"],"prefix":"10.1002","volume":"10","author":[{"given":"Kambiz","family":"Dowlatshahi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julee D.","family":"Bangert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael F.","family":"Haklin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles K.","family":"Rhodes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald S.","family":"Weinstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven G.","family":"Economou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,10,19]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(84)90074-X"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800710211"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800731203"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.40.5.341"},{"key":"e_1_2_1_6_2","first-page":"51","volume-title":"Neodymium:YAG Laser in Medicine and Surgery","author":"Bown SG","year":"1983"},{"key":"e_1_2_1_7_2","first-page":"91","volume-title":"Porphyrin Localization and Treatment of Tumors","author":"Svaasand LO","year":"1984"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900080306"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.163.1.3823432"},{"key":"e_1_2_1_10_2","first-page":"173","article-title":"Artificial sapphire probe for contact photo\u2010coagulation and tissue vaporization with the Nd:YAG laser","volume":"19","author":"Daikuzono N","year":"1985","journal-title":"Med Instrum"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.163.1.3823433"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900080509"},{"key":"e_1_2_1_13_2","first-page":"1690","article-title":"Lifetime dose\u2010response relationships for mammary tumor induction by a single administration of N\u2010methyl\u2010N\u2010nitro\u2010surea","volume":"41","author":"McCormick DL","year":"1981","journal-title":"Cancer Res"},{"key":"e_1_2_1_14_2","first-page":"1663","article-title":"In depth radiation therapy by YAG laser for malignant tumors in the liver under ultrasonic imaging (abstr)","volume":"88","author":"Hashimoto D","year":"1985","journal-title":"Gastroenterology"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(87)90918-8"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.1900100404","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.1900100404","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T20:32:42Z","timestamp":1698006762000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.1900100404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,1]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1990,1]]}},"alternative-id":["10.1002\/lsm.1900100404"],"URL":"https:\/\/doi.org\/10.1002\/lsm.1900100404","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,1]]}}}