{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T18:16:21Z","timestamp":1759774581793},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,10,19]],"date-time":"2005-10-19T00:00:00Z","timestamp":1129680000000},"content-version":"vor","delay-in-days":5405,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[1991,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Conventional hyperthermia treatment of superficial tumors in the oral cavity is troublesome due to difficulty in accessing the lesion. A new hyperthermia technique employing near\u2010infrared radiation delivered through a flexible silica optical fiber is described. The system consisted of an Nd:YAG laser for tissue heating, a He\u2013Ne laser for aiming beam, a computer\u2010controlled optical shutter, an interstitial thermometer, computer, and a printer. A 3\u2010m\u2010long 600\u2010\u03bcm silica fiber delivered laser energy to the tumor via surface illumination. Using the aiming beam, the spot size was adjusted to include 5 mm of surrounding normal tissue. A thermocouple implanted in the tumor base provided temperature feedback to maintain desired hyperthermic temperature within the lesion.<\/jats:p><jats:p>Three spontaneously occurring canine (two squamous cell carcinomas on the gum, one pigmented melanoma on the hard palate) and one feline tumor (squamous cell carcinoma on the nose) have been treated with Nd:YAG laser hyperthermia. Hyperthermia was delivered at 43.5\u00b0C for 1 h. All animals received standard radiation treatment prior to hyperthermia. Nd:YAG laser hyperthermia allowed effective and efficient delivery of heat to veterinary nasal and oral lesions otherwise not treatable with conventional heating techniques.<\/jats:p>","DOI":"10.1002\/lsm.1900110407","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T13:37:33Z","timestamp":1172929053000},"page":"351-355","source":"Crossref","is-referenced-by-count":7,"title":["Nd:YAG laser\u2010induced hyperthermia treatment of spontaneously occurring veterinary head and neck tumors"],"prefix":"10.1002","volume":"11","author":[{"given":"Masoud","family":"Panjehpour","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bergein F.","family":"Overholt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donita L.","family":"Frazier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward R.","family":"Klebanow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,10,19]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4684-4193-2"},{"key":"e_1_2_1_3_2","first-page":"2264","article-title":"Potential for therapy of drugs and hyperthermia","volume":"39","author":"Hahn GM","year":"1979","journal-title":"Cancer Res"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-54-642-443"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900080510"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900100106"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900050607"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900070413"},{"key":"e_1_2_1_9_2","doi-asserted-by":"crossref","unstructured":"PanjehpourM MilliganAJ OverholtBF:Interstitial hyperthermia treatment using Nd: YAG laser. In: Berry MJ Harpole GM eds. \u201cThermal and Optical Interactions with Biological and Related Composite Materials.\u201d Proceedings of SPIE Meeting Los Angeles California Vol. 1064.1989 pp125\u2013130.","DOI":"10.1117\/12.951956"},{"key":"e_1_2_1_10_2","unstructured":"PanjehpourM MilliganAJ OverholtBF:Nd: YAG laser\u2010induced interstitial hyperthermia. In: Roemer RB McGrath JJ Bowman HF eds. \u201cBioheat Transfer\u2013Applications in Hyperthermia Emerging Horizons in Instrumentation and Modeling.\u201d Proceedings of the 110th Winter Annual Meeting of American Society of Mechanical Engineers San Francisco California 1989 pp75\u201380."},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900080306"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.1900110407","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.1900110407","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T07:42:34Z","timestamp":1698046954000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.1900110407"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,1]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1991,1]]}},"alternative-id":["10.1002\/lsm.1900110407"],"URL":"https:\/\/doi.org\/10.1002\/lsm.1900110407","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,1]]}}}