{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T20:37:26Z","timestamp":1791751046381,"version":"4.3.4"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,10,19]],"date-time":"2005-10-19T00:00:00Z","timestamp":1129680000000},"content-version":"vor","delay-in-days":4309,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[1994,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A numerical model for thermal damage to human arterial tissue is presented, based on protein denaturation kinetics. The model involves determination of coefficients of rate processes A &amp; \u03b4E, which are tissue type\u2010dependent (arterial tissue in this study), and definition of threshold damage. A feedback\u2010controlled constant surface temperature device was used to induce 80 coagulative lesions of arterial human tissue ranging in temperature from 66\u00b0C to 76\u00b0C and in duration from 15 to 1,500 seconds. The measured coefficients were determined to be A = 5.6 \u00d7 10<jats:sup>63<\/jats:sup>s<jats:sup>\u22121<\/jats:sup>and \u03b4E = 430 KJ mole<jats:sup>\u22121<\/jats:sup>. These numerical values closely approximate the coefficients of the rate process for denaturation of collagen molecules. These and other histological observations strongly suggest collagen to be the primary coagulating component of arterial tissue at the onset of thermal coagulative damage. The ability of this model to predict onset of tissue coagulation during laser coagulation was studied using 10 postmortem human arterial samples exposed to argon laser irradiation. \u00a9 1994 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/lsm.1900150205","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T16:26:49Z","timestamp":1172939209000},"page":"176-184","source":"Crossref","is-referenced-by-count":91,"title":["Rate process model for arterial tissue thermal damage: Implications on vessel photocoagulation"],"prefix":"10.1002","volume":"15","author":[{"given":"Ramtin","family":"Agah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Pearce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley J.","family":"Welch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massoud","family":"Motamedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,10,19]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"489","article-title":"Studies of thermal injury, V. 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