{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T02:57:44Z","timestamp":1773802664255,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,4,24]],"date-time":"2007-04-24T00:00:00Z","timestamp":1177372800000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2007,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objective<\/jats:title><jats:p>Until now, UV lasers could not be applied to vitreoretinal surgery because of the absence of a practical beam guiding system. A flexible, freely mobile hollow core waveguide, capable of delivering UV laser light, was recently developed. We evaluated the feasibility of this UV laser guiding system for vitreoretinal surgery in enucleated porcine and rabbit eyes and in vivo on rabbit retina.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>193\u2010nm argon fluoride (ArF) excimer laser and a 5th harmonic Nd:YAG laser with the wavelength of 213 nm were used as a light source. A hollow core waveguide was connected to a handpiece with a 20\u2010gauge endoprobe as an instrument for vitreoretinal surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Cutting of the retina was possible only with contact technique. With a selected repetition rate of 20 Hz, sharp, full\u2010depth dissection of porcine retinas was achieved only with 1.0 J\/cm<jats:sup>2<\/jats:sup>. With the repetition rate of 50 Hz, even 0.05 J\/cm<jats:sup>2<\/jats:sup> could incise the total thickness of rabbit retina with no histological damage of the underlying retinal pigment epithelium. The ease in using the instrument for vitreoretinal surgery was confirmed by the in vivo experiment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study revealed the potential use of the new type of the UV laser scalpel, connected to a hollow core waveguide, to perform precise, \u201ccold,\u201d and tractionless cutting during vitreoretinal surgery. Lasers Surg. Med. 39: 353\u2013357, 2007. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.20480","type":"journal-article","created":{"date-parts":[[2007,4,24]],"date-time":"2007-04-24T19:48:12Z","timestamp":1177444092000},"page":"353-357","source":"Crossref","is-referenced-by-count":8,"title":["Flexible UV light guiding system for intraocular laser microsurgery"],"prefix":"10.1002","volume":"39","author":[{"given":"Stanislaw","family":"Schastak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yousef","family":"Yafai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsutomu","family":"Yasukawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu\u2010Sheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"Hillrichs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Wiedemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,4,24]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(89)32818-1"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1981.03930020319025"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(75)90862-4"},{"key":"e_1_2_1_5_2","first-page":"14","article-title":"Ultrastructual and electron\u2010immunocytochemical characterization of cells in epiretinal membranes","volume":"31","author":"Vinores SA","year":"1990","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(96)30460-0"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(95)31027-5"},{"key":"e_1_2_1_8_2","first-page":"1825","article-title":"Vitreoretinal surgery assisted by the 193\u2010nm excimer laser","volume":"38","author":"Hemo I","year":"1997","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_1_9_2","first-page":"3835","article-title":"Vitreoretinal ablation in fluid media with 193 nm excimer laser beam","volume":"35","author":"Palanker D","year":"1994","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_1_10_2","first-page":"1667","article-title":"Experimental ocular surgery with a high\u2010repetition\u2010rate erbium:YAG laser","volume":"39","author":"Brazitikos PD","year":"1998","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_1_11_2","first-page":"2752","article-title":"Investigation of corneal ablation efficiency using 213\u2010nm solid state laser pulses","volume":"90","author":"Dair GT","year":"1999","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.119.4.533"},{"key":"e_1_2_1_13_2","doi-asserted-by":"crossref","first-page":"529","DOI":"10.3928\/1081-597X-20020901-07","article-title":"Cytotoxic and mutagenic action of 193\u2010nm and 213\u2010nm laser radiation","volume":"18","author":"Kaido TJ","year":"2002","journal-title":"J Refract Surg"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.20480","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.20480","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T04:22:11Z","timestamp":1700022131000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.20480"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,4]]}},"alternative-id":["10.1002\/lsm.20480"],"URL":"https:\/\/doi.org\/10.1002\/lsm.20480","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,4]]}}}