{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:44:32Z","timestamp":1790786672099,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2007,9,20]],"date-time":"2007-09-20T00:00:00Z","timestamp":1190246400000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2007,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objective<\/jats:title><jats:p>Two laser devices that are used today in endoscopic treatment of renal and ureteral calculi are the frequency\u2010doubled double\u2010pulse neodynium:YAG (FREDDY) and Holmium:YAG lasers. The mechanism of action of these lasers differs, thus conferring potentially different safety and efficacy profiles. The in vitro efficacy of these lasers in treating urinary stones has been explored, but to our knowledge no study compares the in vivo efficacy. The purpose of this study is to compare the stone\u2010free and complication rates of the FREDDY and holmium lasers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design\/Materials and Methods<\/jats:title><jats:p>Subjects were included in the study (from January 2004 to September 2006) if they had adequate documentation of stone size and location, postoperative stone burden, and perioperative complications. Stone\u2010free status was determined based on intraoperative findings and postoperative imaging. Complications included bleeding, ureteral perforation, any intraoperative event necessitating termination of the procedure, ureteral stricture, hydronephrosis, and admission to the hospital with a diagnosis related to the procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty patients with adequate follow\u2010up were identified. Thirty patients were treated with FREDDY and 30 patients with Holmium laser. Fisher's exact test was employed for statistical analysis. There was no significant difference in the average stone size between the FREDDY and Holmium groups, which were 6.7 mm and 6.1 mm, respectively. Stone\u2010free rates in the FREDDY and Holmium groups were 76.7% and 93.3%, respectively, <jats:italic>P<\/jats:italic>\u2009=\u20090.149. The complication rates were 17.4% in the FREDDY group and 10% in the Holmium group, <jats:italic>P<\/jats:italic>\u2009=\u20090.667.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The complication and stone\u2010free rates did not significantly differ between the FREDDY and Holmium lasers, though there was a trend toward a higher stone\u2010free rate and lower complication rate with the holmium laser. Holmium laser may be more effective than the FREDDY laser in fragmenting calcium oxalate monohydrate stones. The device and laser fiber costs were comparable. Lasers Surg. Med. 39:637\u2013640, 2007. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.20545","type":"journal-article","created":{"date-parts":[[2007,9,20]],"date-time":"2007-09-20T18:47:46Z","timestamp":1190314066000},"page":"637-640","source":"Crossref","is-referenced-by-count":30,"title":["A comparison of the FREDDY and holmium lasers during ureteroscopic lithotripsy"],"prefix":"10.1002","volume":"39","author":[{"given":"Jennifer","family":"Yates","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"August","family":"Zabbo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gyan","family":"Pareek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,9,20]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)91667-3"},{"key":"e_1_2_1_3_2","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/S0022-5347(17)44043-2","article-title":"Pulsed dye laser fragmentation of ureteral calculi: Initial clinical experience","volume":"187","author":"Dretler SP","year":"1987","journal-title":"J Urol"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-007-0163-x"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.2006.20.296"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.11.078"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9101(1999)25:1<38::AID-LSM5>3.0.CO;2-L"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900120402"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.1999.13.181"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9101(1996)18:3<278::AID-LSM10>3.0.CO;2-2"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(96)00158-6"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)65661-1"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2007.04.029"},{"key":"e_1_2_1_14_2","first-page":"362A","article-title":"First clinical experiences of laser lithotripsy using the partially frequency\u2010doubled double\u2010pulse neodynium:YAG laser (\u201cFREDDY\u201d) (abstract)","volume":"165","author":"Stark L","year":"2001","journal-title":"J Urol"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000154341.08206.69"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.20545","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.20545","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T12:29:48Z","timestamp":1700051388000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.20545"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9]]},"references-count":14,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["10.1002\/lsm.20545"],"URL":"https:\/\/doi.org\/10.1002\/lsm.20545","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,9]]}}}