{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T18:17:30Z","timestamp":1790014650430,"version":"4.0.1"},"reference-count":70,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2010,2,17]],"date-time":"2010-02-17T00:00:00Z","timestamp":1266364800000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Intense pulsed light (IPL) devices use flashlamps and bandpass filters to emit polychromatic incoherent high\u2010intensity pulsed light of determined wavelength spectrum, fluence, and pulse duration. Similar to lasers, the basic principle of IPL devices is a more or less selective thermal damage of the target. The combination of prescribed wavelengths, fluences, pulse durations, and pulse intervals facilitates the treatment of a wide spectrum of skin conditions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To summarize the physics of IPL, to provide guidance for the practical use of IPL devices, and to discuss the current literature on IPL in the treatment of unwanted hair growth, vascular lesions, pigmented lesions, acne vulgaris, and photodamaged skin and as a light source for PDT and skin rejuvenation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic search of several electronic databases, including Medline and PubMed and the authors experience on intense pulsed light.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Numerous trials show the effectiveness and compatibility of IPL devices.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Most comparative trials attest IPLs similar effectiveness to lasers (level of evidence: 2b to 4, depending on the indication). However, large controlled and blinded comparative trials with an extended follow\u2010up period are necessary. Lasers Surg. Med. 42:93\u2013104, 2010. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.20877","type":"journal-article","created":{"date-parts":[[2010,2,17]],"date-time":"2010-02-17T20:07:40Z","timestamp":1266437260000},"page":"93-104","source":"Crossref","is-referenced-by-count":278,"title":["Intense pulsed light (IPL): A review"],"prefix":"10.1002","volume":"42","author":[{"given":"Philipp","family":"Babilas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Schreml","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf\u2010Markus","family":"Szeimies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Landthaler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,2,17]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"91","article-title":"Treatment of capillary hemangiomas and nevi flammei with light","author":"Muhlbauer W","year":"1976","journal-title":"Langenbecks Arch Chir"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.6836297"},{"key":"e_1_2_1_4_2","first-page":"503","article-title":"Treatment of benign vascular lesions with the photoderm VL high\u2010intensity pulsed light source","volume":"13","author":"Goldman MP","year":"1997","journal-title":"Adv Dermatol"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-008-9161-7"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/14764170802275832"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-007-0517-z"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.136.9.1152"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1080\/14764170701280693"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1988.01670060015008"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2008.34233.x"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-007-0510-6"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20584"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-006-0373-2"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1080\/14764170600717902"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2005.01327.x"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1080\/146288300750163745"},{"issue":"3","key":"e_1_2_1_18_2","first-page":"273","article-title":"Skin rejuvenation in Asian skin: The analysis of clinical effects and basic mechanisms of intense pulsed light","volume":"7","author":"Feng Y","year":"2008","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1080\/09546630802132627"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1080\/09546630802178224"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20485"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2008.02944.x"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2009.01089.x"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2008.34130.x"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20603"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2008.34126.x"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2008.34184.x"},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2008.34274.x"},{"key":"e_1_2_1_29_2","doi-asserted-by":"publisher","DOI":"10.1159\/000182252"},{"key":"e_1_2_1_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20408"},{"key":"e_1_2_1_31_2","doi-asserted-by":"publisher","DOI":"10.1159\/000151273"},{"key":"e_1_2_1_32_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2005.31204"},{"key":"e_1_2_1_33_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08702.x"},{"key":"e_1_2_1_34_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.135.6.679"},{"issue":"1","key":"e_1_2_1_35_2","first-page":"7","article-title":"Intense pulsed light source for the treatment of dye laser resistant port\u2010wine stains","volume":"5","author":"Bjerring P","year":"2003","journal-title":"J Cosmet Laser Ther"},{"key":"e_1_2_1_36_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2004.30260.x"},{"key":"e_1_2_1_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2005.04.006"},{"key":"e_1_2_1_38_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1473-2165.2008.00375.x"},{"key":"e_1_2_1_39_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1473-2165.2005.00202.x"},{"key":"e_1_2_1_40_2","doi-asserted-by":"publisher","DOI":"10.1080\/14764170701846907"},{"key":"e_1_2_1_41_2","doi-asserted-by":"publisher","DOI":"10.1080\/09546630601028752"},{"key":"e_1_2_1_42_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2006.06013.x"},{"key":"e_1_2_1_43_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02156762"},{"key":"e_1_2_1_44_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08993.x"},{"key":"e_1_2_1_45_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20638"},{"key":"e_1_2_1_46_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2009.01156.x"},{"key":"e_1_2_1_47_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09104.x"},{"key":"e_1_2_1_48_2","doi-asserted-by":"publisher","DOI":"10.1080\/14764170160260744"},{"key":"e_1_2_1_49_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.sap.0000196579.14954.d6"},{"key":"e_1_2_1_50_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1473-2130.2004.00071.x"},{"issue":"2","key":"e_1_2_1_51_2","first-page":"51","article-title":"Utilization of intense pulsed light in the treatment of face and neck erythrosis","volume":"49","author":"Madonna Terracina FS","year":"2007","journal-title":"Acta Chir Plast"},{"key":"e_1_2_1_52_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-59410-6_28"},{"key":"e_1_2_1_53_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2005.00147.x"},{"issue":"4","key":"e_1_2_1_54_2","first-page":"340","article-title":"Photodynamic therapy in dermatology","volume":"16","author":"Babilas P","year":"2006","journal-title":"Eur J Dermatol"},{"key":"e_1_2_1_55_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31816b1300"},{"key":"e_1_2_1_56_2","doi-asserted-by":"publisher","DOI":"10.1039\/b823378k"},{"key":"e_1_2_1_57_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.07959.x"},{"key":"e_1_2_1_58_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2005.31003"},{"key":"e_1_2_1_59_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2006.32163.x"},{"key":"e_1_2_1_60_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-006-0420-z"},{"key":"e_1_2_1_61_2","article-title":"Phototherapy, photodynamic therapy and lasers in the treatment of acne","author":"Degitz K","year":"2009","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_1_62_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20469"},{"issue":"7","key":"e_1_2_1_63_2","first-page":"627","article-title":"Phototherapy in the treatment of acne vulgaris","volume":"7","author":"Sami NA","year":"2008","journal-title":"J Drugs Dermatol"},{"issue":"10","key":"e_1_2_1_64_2","first-page":"1010","article-title":"A comparison of intense pulsed light, combination radiofrequency and intense pulsed light, and blue light in photodynamic therapy for acne vulgaris","volume":"6","author":"Taub AF","year":"2007","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_1_65_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2007.33142.x"},{"key":"e_1_2_1_66_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20634"},{"key":"e_1_2_1_67_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20000"},{"key":"e_1_2_1_68_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.142.8.985"},{"key":"e_1_2_1_69_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2008.34309.x"},{"key":"e_1_2_1_70_2","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0b013e3180327943"},{"key":"e_1_2_1_71_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2008.34144.x"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.20877","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.20877","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.20877","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T11:54:11Z","timestamp":1700654051000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.20877"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":70,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["10.1002\/lsm.20877"],"URL":"https:\/\/doi.org\/10.1002\/lsm.20877","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,2]]}}}