{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T02:51:09Z","timestamp":1787799069251,"version":"build-2784847793"},"reference-count":12,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2010,6,25]],"date-time":"2010-06-25T00:00:00Z","timestamp":1277424000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2010,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objective<\/jats:title><jats:p>Tuberous sclerosis (TS) is a well\u2010described genetic disorder that is classically associated with up to hundreds of facial angiofibromas. Due to the progressive nature of the skin lesions and the early clinical presentation, a safe and effective technique for treating these disfiguring skin lesions is needed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design\/Patients and Methods<\/jats:title><jats:p>We report a combinatorial technique for treating the angiofibromas of TS. We present a case series of three TS patients treated with this technique combining pinpoint electrosurgery, pulsed\u2010dye laser treatment, and ablative fractional resurfacing (AFR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In all presented cases, improvement in the number and appearance of facial angiofibromas and erythema is noted. No scarring or adverse events were reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The technique of electrosurgery, pulsed\u2010dye laser treatment, and AFR represents a new and safe therapeutic option for treating facial angiofibromas associated with TS. Lasers Surg. Med. 42:357\u2013360, 2010. \u00a9 2010 Wiley\u2013Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.20939","type":"journal-article","created":{"date-parts":[[2010,6,26]],"date-time":"2010-06-26T20:21:09Z","timestamp":1277583669000},"page":"357-360","source":"Crossref","is-referenced-by-count":31,"title":["New technique using combined pulsed dye laser and fractional resurfacing for treating facial angiofibromas in tuberous sclerosis"],"prefix":"10.1002","volume":"42","author":[{"given":"Elliot T.","family":"Weiss","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy G.","family":"Geronemus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,6,25]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61279-9"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-200103000-00022"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1997.tb00677.x"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1998.tb04161.x"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-198805000-00005"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/019459988609400106"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1994.tb03709.x"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.04968.x"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.116223"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-7310(05)73121-5"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20659"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2009.358"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.20939","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.20939","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T05:16:22Z","timestamp":1696914982000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.20939"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6,25]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["10.1002\/lsm.20939"],"URL":"https:\/\/doi.org\/10.1002\/lsm.20939","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6,25]]}}}