{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:34:04Z","timestamp":1773282844216,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2010,9,29]],"date-time":"2010-09-29T00:00:00Z","timestamp":1285718400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2010,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objective<\/jats:title><jats:p>Anatomic, tissue ablation and coagulation, and histopathologic outcomes of the 150\u2010W 980\u2010nm diode laser selective light vaporization (SLV\u2122) of the prostate in the first survival study of living canines were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design\/Materials and Methods<\/jats:title><jats:p>Ten dogs underwent anterograde SLV\u2122 with the 150\u2010W 980\u2010nm laser delivered by its side\u2010firing fiber (Fusion\u2122). Postoperatively, two dogs were euthanized at 3\u2009hours as planned, six at 2\u20137 days due to complications, and two, without complications, at 8 weeks as planned. Laser energy and time were recorded. Prostates were sectioned, measured, and histologically analyzed after hematoxylin and eosin (H&amp;E), triphenyltetrazolium chloride (TTC), or Gomori trichrome (GT) staining.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>SLV\u2122 acutely and hemostatically created a 0.6\u2009\u00b1\u20090.3\u2009cm<jats:sup>3<\/jats:sup> cavity in the 3\u2010hour group accompanied by H&amp;E\u2010 and TTC\u2010identified coagulation necrosis of up to 9.5\u2009mm (6.1\u2009\u00b1\u20091.2\u2009mm) that led to prostatic slough\u2010induced obstruction and perforation in six of eight (75%) surviving animals, necessitating unplanned euthanasia within 2\u20137 days. H&amp;E\u2010 and GT\u2010stained prostates at 8 weeks postoperatively showed large (9.6\u2009\u00b1\u20091.4\u2009cm<jats:sup>3<\/jats:sup>) re\u2010epithelialized prostatic cavities with persistent diffuse interstitial Prostatitis and collagenous fibrosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>SLV\u2122 with the 150\u2010W 980\u2010nm diode laser in living canines produced small cavities acutely, and was accompanied by deeply necrotic prostatic slough\u2010induced obstruction and perforation in a majority of animals. A minority survived SLV and had favorable anatomic outcomes whereas histology revealed persisting inflammation. Further in vivo studies and a cautious clinical approach are recommended to finally evaluate the potential of SLV\u2122 with the 150\u2010W 980\u2010nm diode laser. Lasers Surg. 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