{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T15:45:59Z","timestamp":1790091959003,"version":"4.0.1"},"reference-count":26,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2011,1,18]],"date-time":"2011-01-18T00:00:00Z","timestamp":1295308800000},"content-version":"vor","delay-in-days":48,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Non\u2010ablative fractional resurfacing (NA FR) has been shown to be effective for photorejuvenation and acne scarring. Previous studies indicated that density, more than pulse energy, was associated with post\u2010inflammatory hyperpigmentation (PIH) in Asians. The objective of this retrospective study was to assess the efficacy and complications of eight passes of NA FR (\u2018full\u2010NA FR\u2019) with the 1,550\u2009nm erbium\u2010doped fibre fractional laser (Fraxel SR laser system, Solta Medical, Hayward, CA) versus four passes (\u2018mini\u2010NA FR\u2019) with comparable pulse energy and treatment level as \u2018full\u2010NA FR\u2019, but double the number of treatment sessions in Asian acne scar patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Forty\u2010seven Asian atrophic facial acne scar patients who received full\u2010face full\u2010NA FR or mini\u2010NA FR treatments between December 2005 and February 2009 were included. All photographic images captured with the Canfield Visia CR system at baseline and follow\u2010ups were assessed for clinical efficacy and complications by an independent, non\u2010treating and blinded physician.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The total treatment densities for full\u2010NA FR and mini\u2010NA FR were 442.5 and 210.5\u2009MTZ\/cm<jats:sup>2<\/jats:sup>, respectively. For full\u2010NA FR, the PIH risk was 18.2% with cross\u2010polarized images compared to 6.0% for mini\u2010NA FR. This difference was statistically significant (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Improvement in skin texture, acne scarring, enlarged pores and overall pigmentation irregularity all reached statistical significance at last follow\u2010up compared to baseline. There was no statistically significant difference in clinical efficacy between three full\u2010NA FR and six mini\u2010NA FR treatments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>NA FR was effective and safe in Asians. By reducing the number of passes and the total treatment density, the risk of PIH could be reduced. Meanwhile, clinical efficacy could be maintained by increasing the total number of treatment sessions. Lasers Surg. 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