{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T07:51:10Z","timestamp":1780386670766,"version":"3.54.1"},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,6,27]],"date-time":"2013-06-27T00:00:00Z","timestamp":1372291200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction\/Objective<\/jats:title><jats:p>Urinary complications such as bladder outlet obstruction or urinary retention following radiation therapy or brachytherapy have been reported in up to 15% of men. When conservative therapy has failed, surgical intervention with transurethral resection of the prostate (TURP) may be performed, but carries a significant risk of incontinence, ranging from 18% to 70% in reported literature. We reviewed a cohort of men previously treated with radiation or brachytherapy, who underwent laser prostatectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From February 2004 to October 2011, 12 patients (Six\u2009=\u2009brachytherapy and Six\u2009=\u2009external beam radiation) underwent 532\u2009nm GreenLight\u2122 laser prostatectomy by a single surgeon (BBC) for chronic retention or debilitating obstructive symptoms. Preoperative, intraoperative, and postoperative parameters were collected prospectively and reviewed retrospectively. Statistical analysis was performed with a Wilcox Rank sum test with significance defined as <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median patient age was 77.4 (Interquartile range (IQR) 73.9, 79.1). Prior to surgery, five patients were catheter dependent. Intraopertively, the median operative time was 48\u2009minutes (IQR 35, 67); median lasing time was 28\u2009minutes (IQR 23, 44); median Joules used was 126,873 (IQR 95,030, 222,336) J. Postoperative median follow up was 22.9 (IQR 13.4, 41.7) months. Significant improvements were noted in IPSS, QoL scores, PVR, and <jats:italic>Q<\/jats:italic><jats:sub>max<\/jats:sub> after PVP treatment. At 12 months, the median decrease in IPSS, QoL scores, and PVR was 15 (IQR 14.5, 22) to 10 (IQR 5.5, 13.5), 5 (IQR 3.5, 5) to 2 (IQR 1, 3.5), 200 (IQR 171, 327.5) to 5 (IQR 1.25, 8), respectively (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05 for all). Similarly, at 12 months, the median increase in <jats:italic>Q<\/jats:italic><jats:sub>max<\/jats:sub> (ml\/second) was 4 (IQR 3, 10) to 15.9 (IQR 11, 16) (<jats:italic>P<\/jats:italic>\u2009=\u20090.04). There were no reportable complications at 12 months. None of the 12 patients that underwent 532\u2009nm GreenLight\u2122 laser prostatectomy developed stress urinary incontinence. One patient developed metastatic prostate cancer and the remaining patients had no evidence of biochemical recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this pilot study, 532\u2009nm GreenLight\u2122 laser prostatectomy is feasible and safe in patients who have undergone prior radiotherapy for prostate cancer. Laser prostatectomy provides a durable response while maintaining continence in this cohort suffering from severe lower urinary tract symptoms (LUTS) or retention. Larger, randomized trials comparing GreenLight\u2122 laser prostatectomy to traditional TURP are necessary to confirm non\u2010inferiority. Lasers Surg. Med. 45:358\u2013361, 2013. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.22152","type":"journal-article","created":{"date-parts":[[2013,6,27]],"date-time":"2013-06-27T16:12:37Z","timestamp":1372349557000},"page":"358-361","source":"Crossref","is-referenced-by-count":8,"title":["Evaluation of continence following 532\u2009nm laser prostatectomy for patients previously treated with radiation therapy or brachytherapy"],"prefix":"10.1002","volume":"45","author":[{"given":"David","family":"No","sequence":"first","affiliation":[{"name":"The Commonwealth Medical College 525 Pine St Scranton Pennsylvania 185009"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Charles","family":"Osterberg","sequence":"additional","affiliation":[{"name":"Department of Urology Weill Cornell\u2010New York Presbyterian Hospital Starr 900, 525 E. 68th Street New York New York 10065"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon","family":"Otto","sequence":"additional","affiliation":[{"name":"Department of Urology Weill Cornell\u2010New York Presbyterian Hospital Starr 900, 525 E. 68th Street New York New York 10065"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izolda","family":"Naftali","sequence":"additional","affiliation":[{"name":"Brooklyn College 2900 Bedford Ave. Brooklyn New York 11210"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Urology Weill Cornell\u2010New York Presbyterian Hospital Starr 900, 525 E. 68th Street New York New York 10065"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,6,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)02658-X"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)38171-5"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(97)00928-0"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000132136.95221.63"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000152698.20487.0e"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1089\/end.2010.0512"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.01.068"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eursup.2008.01.012"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)65871-5"},{"key":"e_1_2_7_11_1","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/S0022-5347(17)49985-X","article-title":"Radiation therapy in carcinoma of the prostate: A contributing cause of urinary incontinence","volume":"132","author":"Kaufman JJ","year":"1984","journal-title":"J Urol"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2008.08.057"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)62542-4"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)56765-8"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)39438-7"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9098(199702)64:2<127::AID-JSO7>3.0.CO;2-D"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.22152","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.22152","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.22152","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T13:47:20Z","timestamp":1696513640000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.22152"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,27]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.1002\/lsm.22152"],"URL":"https:\/\/doi.org\/10.1002\/lsm.22152","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,27]]}}}