{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T13:08:42Z","timestamp":1773666522050,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,2,24]],"date-time":"2014-02-24T00:00:00Z","timestamp":1393200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:sec><jats:title>Background and Objective<\/jats:title><jats:p>To examine the possibilities of laser thermoplasty of whole costal cartilages for correction the human congenital chest wall deformities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design\/Materials and Methods<\/jats:title><jats:p><jats:italic>Ex vivo<\/jats:italic> the samples of porcine costal cartilages were heated with lasers of differing wavelengths, including a 0.97\u2010\u03bcm diode laser, a 1.56\u2010\u03bcm erbium\u2010doped quartz fiber laser, and a 1.68\u2010\u03bcm fiber Raman laser. The dynamics of the temperature fields and the degradation of collagen in the laser\u2010affected regions of samples were determined by using, respectively, thermometry, trypsin treatment, and light microscopy<jats:italic>. Ex vivo<\/jats:italic> the whole mechanically deformed costal cartilages of pigs were treated by laser radiation with wavelength 1.68\u2010\u03bcm. The changes of cartilage shape were recorded at certain intervals over a 24\u2010hour period by photographing them in a fixed position with a digital camera.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Treatment of costal cartilage samples from 5 to 11\u2009mm in thickness by laser radiation with 0.97, 1.56, and 1.68\u2009\u03bcm wavelengths showed that the 1.68\u2010\u03bcm radiation could produce the necessary nonuniform bulk heating of the exposed sample. The altered shape of costal cartilage proved to remain stable after treatment when the laser irradiation settings used provided for the heating of a broad region within the tissue to temperatures about 80\u00b0C.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study demonstrates the possibilities of laser thermoplasty of whole costal cartilages for treatment of human congenital chest wall deformities. The development of novel approaches based on laser cartilage engineering techniques will enable to treat the human congenital chest wall deformities. Lasers Surg. Med. 46:302\u2013309, 2014. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.22233","type":"journal-article","created":{"date-parts":[[2014,2,24]],"date-time":"2014-02-24T18:27:32Z","timestamp":1393266452000},"page":"302-309","source":"Crossref","is-referenced-by-count":6,"title":["Ex vivo laser thermoplasty of whole costal cartilages"],"prefix":"10.1002","volume":"46","author":[{"given":"Alexander P.","family":"Sviridov","sequence":"first","affiliation":[{"name":"Institute on Laser and Information Technologies Russian Academy of Sciences Moscow Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga L.","family":"Zakharkina","sequence":"additional","affiliation":[{"name":"Institute on Laser and Information Technologies Russian Academy of Sciences Moscow Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia Yu.","family":"Ignatieva","sequence":"additional","affiliation":[{"name":"Institute on Laser and Information Technologies Russian Academy of Sciences Moscow Russia"},{"name":"Chemical Department M.V. 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