{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T11:39:11Z","timestamp":1792064351264,"version":"4.4.0"},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,2,2]],"date-time":"2015-02-02T00:00:00Z","timestamp":1422835200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Lutronic, Inc"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Persistent post\u2010acne erythema is one of the most common aesthetic sequelae to arise after active acne resolves. The treatment remains challenging due to lack of effective laser modalities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the safety and efficacy of a low\u2010fluence 585\u2009nm Q\u2010switched Nd:YAG laser for the treatment of post\u2010acne erythema.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials &amp; Methods<\/jats:title><jats:p>Twenty\u2010five patients with post\u2010acne erythema were treated with a low\u2010fluence Q\u2010switched Nd:YAG laser using the 585\u2009nm Gold Toning\u2122 handpiece (5\u2009mm spot size, 5\u201310\u2009ns, 0.30\u20130.55\u2009J\/cm<jats:sup>2<\/jats:sup>, 2\u20134 passes) for three sessions at 2\u2010week intervals. Erythema lesion (macules) count, inflammatory acne (papules, pustules) count, erythema index, degree of post\u2010acne erythema and overall improvement in post\u2010acne erythema and acne scar were assessed at baseline, every 2 weeks and 6 weeks after the last treatment. Subjective degrees of satisfaction were also evaluated. Adverse events were recorded and pain was scored using a visual analog scale (VAS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 6 weeks after 3 sessions of laser treatment, all patients demonstrated clinical improvement. Erythema lesion counts decreased by 20.1% (versus baseline) after the first treatment (<jats:italic>P<\/jats:italic>\u2009=\u20090.004), by 32.7% after the second treatment, by 46.5% at 2 weeks after the third treatment and by 58.7% at the 6\u2010week follow\u2010up (all<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Significant improvements were also noted in erythema indices (22.29\u2009\u00b1\u20092.4 to 17.51\u2009\u00b1\u20091.8) and mean post\u2010acne erythema scores after the first treatment (both<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). The mean scores of independent physician assessments were 4.04\u2009\u00b1\u20090.9 in term of the improvement of post\u2010acne erythema and 3.44\u2009\u00b1\u20090.9 in the improvement of scaring. In addition, we could observe a significant decrease in inflammatory acne lesion counts after two laser treatments with a decrease in mean lesion counts by 67% at the 6\u2010week follow\u2010up. Treatment was well\u2010tolerated and adverse effects were limited to transient erythema and edema at treatment sites.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Low\u2010fluence 585\u2009nm Q\u2010switched Nd:YAG laser treatment is safe and effective for the treatment of post\u2010acne erythema with minimal discomfort and quantifiable improvement in the appearance of early acne scarring and inflammatory acne. Lasers Surg. Med. 47:148\u2013155, 2015. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.22321","type":"journal-article","created":{"date-parts":[[2015,2,2]],"date-time":"2015-02-02T16:42:11Z","timestamp":1422895331000},"page":"148-155","source":"Crossref","is-referenced-by-count":29,"title":["Low\u2010fluence 585 nm Q\u2010switched Nd:YAG laser: A novel laser treatment for post\u2010acne erythema"],"prefix":"10.1002","volume":"47","author":[{"given":"Ratchathorn","family":"Panchaprateep","sequence":"first","affiliation":[{"name":"Division of Dermatology Department of Medicine King Chulalongkorn Memorial Hospital Chulalongkorn University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Girish","family":"Munavalli","sequence":"additional","affiliation":[{"name":"Dermatology, Laser and Vein Specialists of Carolinas Charlotte North 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