{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T19:53:33Z","timestamp":1783626813675,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,7,14]],"date-time":"2015-07-14T00:00:00Z","timestamp":1436832000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Syneron\/Candela"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Although nanosecond\u2010domain lasers have been the mainstay of laser tattoo removal for decades, recent disruptive innovations in laser design have introduced a new class of commercial Q\u2010switched lasers that generate picosecond\u2010domain pulses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study<\/jats:title><jats:p>A picosecond\u2010domain, Nd:YAG laser with a KTP frequency\u2010doubling crystal was used to treat 31 decorative tattoos in 21 subjects. Safety and effectiveness were determined by blinded evaluation of digital images in this prospective clinical study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average clearance overall as evaluated by blinded observers evaluating randomized digital photographs was 79\u2009\u00b1\u20090.9% (mean\u2009\u00b1\u2009sem) after an average of 6.5 treatments. Of the 31 tattoos completing treatment, 6 had evidence of mild hyper\u2010 or hypo\u2010pigmentation by evaluation of photographs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The 350 picosecond, 532\u2009nm, and 450 picosecond 1,064\u2009nm Nd:YAG laser is safe and effective for removing decorative tattoos. Lasers Surg. Med. 47:542\u2013548, 2015. \u00a9 2015 The Authors. <jats:italic>Lasers in Surgery and Medicine<\/jats:italic> Published by Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.22391","type":"journal-article","created":{"date-parts":[[2015,7,14]],"date-time":"2015-07-14T19:35:08Z","timestamp":1436902508000},"page":"542-548","source":"Crossref","is-referenced-by-count":78,"title":["A novel dual\u2010wavelength, Nd:YAG, picosecond\u2010domain laser safely and effectively removes multicolor tattoos"],"prefix":"10.1002","volume":"47","author":[{"given":"Eric F.","family":"Bernstein","sequence":"first","affiliation":[{"name":"Main Line Center for Laser Surgery Ardmore Pennsylvania 19003"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin T.","family":"Schomacker","sequence":"additional","affiliation":[{"name":"Syneron\u2010Candela Corporation 530 Boston Post Road Wayland Massachusetts 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