{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T13:51:47Z","timestamp":1762955507123},"reference-count":29,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2015,9,28]],"date-time":"2015-09-28T00:00:00Z","timestamp":1443398400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"CNPq and FAPEMIG"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Adhesions commonly occur after abdominal surgery and can cause bowel obstruction, chronic abdominal pain, and infertility. Their prevention remains a challenge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the effects of the application of low\u2010level lasers on the prevention of adhesions and scarring of the skin after peritoniectomia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Twenty\u2010four New Zealand breed male rabbits, approximately 2 months of age, were randomly divided into 3 groups (<jats:italic>n\u2009<\/jats:italic>=\u20098): GC\u2014control group not subjected to laser, GL1\u2014group with laser application at a dose of 0.2\u2009J, and GL2\u2014group with laser application at a dose of 3.6\u2009J. All animals received a longitudinal midline incision and a bilateral resection of the peritoneal fragment, measuring 3\u2009\u00d7\u20091\u2009cm<jats:sup>2<\/jats:sup>. The animals received a laser treatment of one application every 24 hours, beginning at the time of surgery and lasting for a period of 4 days. After 14 days post\u2010surgery, the animals were killed and adhesion formation was evaluated qualitatively and quantitatively by means of a laparotomy shaped inverted \u201cU\u201d, which allowed for the verification of the broad wall of the abdominal cavity and organs. Differences were considered significant at <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The adhesion formation was observed in 100% of the rabbits from groups GC and GL1, as compared to 37.5% of the rabbits from group GL2 (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). The evaluation of the vascularization and tenacity of adhesions among the groups showed no significant difference. In groups CG and GL1, 72% and 83% of adhesions were verified between visceras, respectively whereas in GL2 occurred among abdominal wall. The tensile strength of the skin between the groups was not significant (<jats:italic>P<\/jats:italic>\u2009=\u20090.3106). The resistance of abdominal wall segments without skin he resistance of skin segments between groups GL2 and GC were higher than in GL1 (<jats:italic>P<\/jats:italic>\u2009=\u20090.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Low\u2010level LASER is effective in preventing intra\u2010abdominal adhesions in rabbits without compromising strength and healing of the abdominal wall. Lasers Surg. Med. 47:817\u2013823, 2015. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.22423","type":"journal-article","created":{"date-parts":[[2015,9,28]],"date-time":"2015-09-28T20:01:52Z","timestamp":1443470512000},"page":"817-823","source":"Crossref","is-referenced-by-count":3,"title":["Prevention of abdominal adhesions and healing skin after peritoniectomy using low level laser"],"prefix":"10.1002","volume":"47","author":[{"given":"Mara L.C.D.","family":"Teixeira","sequence":"first","affiliation":[{"name":"Department of Surgery, Medical School of the Federal University of Minas Gerais Post Graduation Course of Santa Casa de BH Belo Horizonte Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo S.","family":"Vasconcellos","sequence":"additional","affiliation":[{"name":"Department of Surgery, Medical School of the Federal University of Minas Gerais Post Graduation Course of Santa Casa de BH Belo Horizonte 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