{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T14:31:11Z","timestamp":1792074671768,"version":"4.4.0"},"reference-count":15,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2015,9,29]],"date-time":"2015-09-29T00:00:00Z","timestamp":1443484800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:sec><jats:title>Background and Objective<\/jats:title><jats:p>Leishmaniasis is a vector borne disease that can cause disease manifestations that range from localized skin ulceration to lethal visceral disease. With increased global travel, cutaneous leishmaniasis (CL) is becoming more common in developed nations. However, current treatment options are limited.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>We report a 16\u2010year\u2010old female who presented with several non\u2010tender, non\u2010healing CL wounds on her bilateral upper and lower extremities. Ablative fractional laser resurfacing (AFR) was used in conjunction with topical paromomycin via laser\u2010assisted delivery to treat the largest non\u2010healing CL wound on the patient's distal lower extremity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Upon follow\u2010up after two treatments with AFR, the patient's wound healed completely without evidence of infection and with minimal scarring.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>AFR with laser\u2010assisted delivery of topical paromomycin represents a novel treatment option for resistant, non\u2010healing CL wounds. The technique may prove additionally useful for concurrent mitigation of scarring related to CL. Lasers Surg. Med. 47:788\u2013791, 2015. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.22426","type":"journal-article","created":{"date-parts":[[2015,9,30]],"date-time":"2015-09-30T04:25:20Z","timestamp":1443587120000},"page":"788-791","source":"Crossref","is-referenced-by-count":10,"title":["Ablative fractional laser resurfacing with topical paromomycin as adjunctive treatment for a recalcitrant cutaneous leishmaniasis wound"],"prefix":"10.1002","volume":"47","author":[{"given":"Andrew","family":"Basnett","sequence":"first","affiliation":[{"name":"Department of Dermatology Naval Medical Center San Diego California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuyet A.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Division of Pediatric and Adolescent Dermatology Rady Children's Hospital San Diego California"},{"name":"University of California San Diego School of Medicine San Diego California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Cannavino","sequence":"additional","affiliation":[{"name":"University of California San Diego School of Medicine San Diego California"},{"name":"Division of Pediatric Infectious Disease Rady Children's Hospital San Diego California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew C.","family":"Krakowski","sequence":"additional","affiliation":[{"name":"Division of Pediatric and Adolescent Dermatology Rady Children's Hospital San Diego California"},{"name":"University of California San Diego School of Medicine San Diego California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,9,29]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0035671"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2010.06.019"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2013.7761"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-1779"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2015.0645"},{"key":"e_1_2_5_7_1","article-title":"Healing of chronic wounds with adjunctive ablative fractional laser resurfacing in two pediatric patients","author":"Krakowski AC","year":"2015","journal-title":"Lasers Surg Med"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2012.03.001"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1202657"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir496"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03630.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1081\/DDC-120030423"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.3275479"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/2013.jamadermatol.668"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2013.12129"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.21096"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.22426","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.22426","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.22426","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T03:15:58Z","timestamp":1695006958000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.22426"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,29]]},"references-count":15,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["10.1002\/lsm.22426"],"URL":"https:\/\/doi.org\/10.1002\/lsm.22426","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,29]]}}}