{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T04:29:38Z","timestamp":1772684978147,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,10,15]],"date-time":"2018-10-15T00:00:00Z","timestamp":1539561600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>In the recent past, long pulsed dye lasers (LPDL) have been investigated for the treatment of epidermal pigmented lesions (EPLs). Using a pigmented lesion compression headpiece, blood is pushed laterally out of the laser field focusing laser energy on melanin. Recent studies have demonstrated excellent responses using a single\u2010pulse at the following settings: 9\u201312\u2009J\/cm<jats:sup>2<\/jats:sup>, 1.5\u2009milliseconds, 7\u201010\u2009mm spot size with compression. However, the majority of these studies report patients requiring up to four treatments for lesion resolution. Herein, we describe our experiences utilizing a back\u2010to\u2010back double\u2010pulse technique to decrease the total number of treatments needed for EPL clearance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010six patients (27 females, 9 males; skin types I\u2013IV) with benign facial EPLs were included. Each lesion received two back\u2010to\u2010back pulses (fluence of 9\u201312\u2009J\/cm<jats:sup>2<\/jats:sup>, 1.5\u2009milliseconds duration, and 7\u2009mm spot size). If needed, a second treatment was delivered 4\u20138 weeks later. Pre\u2010 and post\u2010photos after the first treatment were evaluated by two independent board\u2010certified dermatologists.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Lesion clearance after the first treatment was graded on a Likert scale as: 1\u2009=\u2009poor (&lt;25% clearance); 2\u2009=\u2009fair (25\u201350%); 3\u2009=\u2009good (51\u201375%); and 4\u2009=\u2009excellent (&gt;75%). Of the 36 participants, 23 had excellent clearing, 10 with good, 2 with fair and 1 with poor clearance. There was only one case of post\u2010inflammatory hyperpigmentation that subsequently resolved, and no cases or scarring or hypopigmentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LPDL with compression continues to be a safe and effective modality for treatment of EPLs. Double\u2010pulsing decreases the total number of treatments needed for lesion resolution, while maintaining safety and potentially decreasing cost. Lasers Surg. Med. 51:136\u2013140, 2019. \u00a9 2018 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23009","type":"journal-article","created":{"date-parts":[[2018,10,15]],"date-time":"2018-10-15T13:42:43Z","timestamp":1539610963000},"page":"136-140","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Long pulsed dye laser with a back\u2010to\u2010back double\u2010pulse technique and compression for the treatment of epidermal pigmented lesions"],"prefix":"10.1002","volume":"51","author":[{"given":"Jessica G.","family":"Labadie","sequence":"first","affiliation":[{"name":"Department of Dermatology Northwestern University Feinberg School of Medicine 676 N. St. Clair Street Suite 1600, Chicago 60611 Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandar L.","family":"Krunic","sequence":"additional","affiliation":[{"name":"Department of Dermatology Northwestern University Feinberg School of Medicine 676 N. St. Clair Street Suite 1600, Chicago 60611 Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,10,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.77552"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.12.043"},{"issue":"1","key":"e_1_2_6_4_1","first-page":"33","article-title":"Solar lentigines: Evaluation pulsed dye laser (LPDL) as an effective treatment option","volume":"4","author":"Ghaninejhadi H","year":"2013","journal-title":"J Lasers Med Sci"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2007.02297.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2007.34035.x"},{"key":"e_1_2_6_7_1","first-page":"945","article-title":"Long\u2010pulse pulsed dye laser delivered with compression for treatment of facial lentigines","volume":"33","author":"Kono T","year":"2007","journal-title":"Dermatol Surg"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20246"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20373"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2008.34126.x"},{"key":"e_1_2_6_11_1","first-page":"18","article-title":"Purpura\u2010free treatment of lentigines using a long\u2010pulsed 595 nm pulsed dye laser with compression handpiece: A randomized, controlled study","volume":"8","author":"Pootongkam S","year":"2009","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20634"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20982"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22582"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22766"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22472"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22454"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22443"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.23009","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.23009","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T04:44:07Z","timestamp":1694666647000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.23009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,15]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["10.1002\/lsm.23009"],"URL":"https:\/\/doi.org\/10.1002\/lsm.23009","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,15]]},"assertion":[{"value":"2018-07-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}