{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T18:22:11Z","timestamp":1793038931115,"version":"4.5.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,10,10]],"date-time":"2018-10-10T00:00:00Z","timestamp":1539129600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study introduces an initial evaluation of a novel High\u2010Intensity Focused Electromagnetic (HIFEM) technology. The primary goal is to quantify any effects the treatments may have on abdominal tissues, as well as to establish hypotheses for future research of this technology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010two patients received four abdominal treatments using the EMSCULPT device (BTL Industries Inc., Boston, MA). Anthropometric evaluations were recorded and digital photographs were taken at baseline, at 2 months, and at 6 months post\u2010treatments. The MRI without contrast determined by vertertebras T12 and S1 (FIESTA and FSPRG sequences) was used to measure dimensions in coronal cross\u2010sectional images of abdominal muscle and fatty tissues, in order to assess any anatomical changes induced by the application.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Analysis of the same MRI slices verified by tissue artefacts showed a statistically significant (all<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001) average 18.6% reduction of adipose tissue thickness, 15.4% increase in rectus abdominis muscle thickness, and 10.4% reduction in rectus abdominus separation (diastasis recti) as measured from the medial border of the muscle 2 months post\u2010treatment. More significant improvements were observed in patients with BMI 18.5\u201324.9 (classified as \u201cnormal\u201d). MRI data from 6\u2010month follow\u2010up suggest the changes can be preserved in longer term. Tape measurements showed on average 3.8\u2009cm subumbilical circumference reduction. The weight of the subjects did not change significantly (average \u22120.5 lb;<jats:italic>P\u2009<\/jats:italic>&gt;\u20090.05). No adverse events were reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>MRI, considered as a highly precise diagnostic method, revealed simultaneous muscle growth, fat reduction and reduced abdominal separation at 2 months and at 6 months post treatments, unrelated with dieting. Further research should investigate the exact physiological processes which stand behind the tissue changes observed in this study. Lasers Surg. Med. 51:40\u201346, 2019. \u00a9 2018 The Authors.<jats:italic>Lasers in Surgery and Medicine<\/jats:italic>Published by Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23024","type":"journal-article","created":{"date-parts":[[2018,10,10]],"date-time":"2018-10-10T07:55:33Z","timestamp":1539158133000},"page":"40-46","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":82,"title":["High intensity focused electromagnetic therapy evaluated by magnetic resonance imaging: Safety and efficacy study of a dual tissue effect based non\u2010invasive abdominal body shaping"],"prefix":"10.1002","volume":"51","author":[{"given":"Brian M.","family":"Kinney","sequence":"first","affiliation":[{"name":"University of Southern California Division of Plastic Surgery Beverly Hills California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Lozanova","sequence":"additional","affiliation":[{"name":"Paula Fines Center Sofia BG Europe"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,10,10]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"The American Society for Aesthetic Plastic Surgery (2016). Cosmetic surgery national data bank statistics.http:\/\/www.surgery.org\/sites\/default\/files\/ASAPS\u2010Stats2016.pdf. Accessed April 25 2017."},{"key":"e_1_2_6_3_1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.25251\/skin.1.1.4","article-title":"Noninvasive body contouring: Literature review and summary of objective data","volume":"1","author":"Bernstein D","year":"2017","journal-title":"SKIN J Cutan Med"},{"key":"e_1_2_6_4_1","article-title":"What are the guidelines for percentage of body fat loss","author":"Muth ND","year":"2009","journal-title":"Am Counc Exerc ACE Ask Expert Blog"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.3121\/cmr.2011.1008"},{"key":"e_1_2_6_6_1","first-page":"317","volume-title":"Handbook of Clinical Neurophysiology","author":"Ziemann U","year":"2004"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.2000.t01-1-00633.x"},{"key":"e_1_2_6_8_1","first-page":"131","article-title":"Cortical excitability and neurology: Insights into the pathophysiology","volume":"27","author":"Badawy RAB","year":"2012","journal-title":"Funct Neurol"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2009.08.016"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/75.6.490"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/63.6.915"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.phm.0000223239.93539.fe"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/jfmk1030328"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(99)00037-0"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2008.09.572"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1991.70.5.1912"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1519\/JSC.0b013e3181e840f3"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00789.2006"},{"key":"e_1_2_6_19_1","first-page":"24","article-title":"Contrasts in muscle and myofibers of elite male and female bodybuilders","volume":"67","author":"Alway SE","year":"1989","journal-title":"J Appl Physiol Bethesda Md 1985"},{"key":"e_1_2_6_20_1","first-page":"67","article-title":"Muscular Function in exercise and training. 3rd International symposium on biological sciences in sport, nice, October\/November 1986","volume":"26","author":"Marconnet P","year":"1987","journal-title":"Med Sport Sci"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00215.2006"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M300190200"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/1743-422X-9-143"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00523.2006"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-511X-11-1"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physio.2013.08.005"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.23024","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.23024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T05:56:47Z","timestamp":1720677407000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.23024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,10]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1002\/lsm.23024"],"URL":"https:\/\/doi.org\/10.1002\/lsm.23024","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,10]]},"assertion":[{"value":"2018-09-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}