{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T19:44:41Z","timestamp":1757706281194},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,7,15]],"date-time":"2019-07-15T00:00:00Z","timestamp":1563148800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004748","name":"Mashhad University of Medical Sciences","doi-asserted-by":"publisher","award":["922071"],"award-info":[{"award-number":["922071"]}],"id":[{"id":"10.13039\/501100004748","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the efficacy of nonablative fractional 1,540\u2009nm laser to treat the atrophic scars caused by the cutaneous leishmaniasis (CL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This clinical trial with a pre\u2010 and a posttreatment measurement was conducted on patients with atrophic CL scars. The lesions were treated with nonablative fractional 1,540\u2009nm laser. We evaluated the patients initially and then monthly, before each treatment session. The final follow\u2010up was done 6 months after the end of study for all patients. Patient assessment was performed by two physicians using the modified Manchester Scar Scale (MSS) as well as the interpretation of captured digital photographs. Moreover, the patients performed a self\u2010assessment by filling in a researcher\u2010made questionnaire. The data were statistically analyzed by SPSS software. <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05 was considered statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty patients with 37 skin lesions participated in the study. The pairwise comparison demonstrated a statistically significant difference between the modified MSS parameters (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05); however, no significant difference was observed between the modified MSS of the third and fourth (<jats:italic>P<\/jats:italic>\u2009=\u20090.82) as well as fourth and fifth (<jats:italic>P<\/jats:italic>\u2009=\u20090.636) sessions. The lesions improvement was significant based on the physician's evaluation (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Furthermore, patients\u2019 level of satisfaction was significantly increased in all six follow\u2010ups (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). No persistent complication was found.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Nonablative fractional 1,540\u2009nm laser is an effective and safe therapeutic choice for atrophic CL, even in darker skins. Lasers Surg. Med. \u00a9 2019 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23136","type":"journal-article","created":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T05:29:23Z","timestamp":1563254963000},"page":"182-187","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Non\u2010Ablative Fractional 1,540\u2010nm Er:Glass Laser in the Treatment of Atrophic Cutaneous Leishmaniasis Scars"],"prefix":"10.1002","volume":"52","author":[{"given":"Ahmad Reza","family":"Taheri","sequence":"first","affiliation":[{"name":"Department of Dermatology, Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences Emam Reza Hospital Mashhad 9137913316 Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vahid","family":"Mashayekhi\u2010Goyonlo","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences Emam Reza Hospital Mashhad 9137913316 Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Salehi","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Research Center for Patient Safety, Mashhad University of Medical Sciences Quaem Hospital Mashhad 9176699199 Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamideh","family":"Mohammadzadeh","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Gonabad University of Medical Sciences, Imam Khomeini Avenue Medical University of Gonabad Gonabad 9691793718 Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,7,15]]},"reference":[{"key":"e_1_2_5_1_2_1","first-page":"171","article-title":"Epidemiology of cutaneous leishmaniasis in Iran: B. Khorassan. Part VI: Cutaneous leishmaniasis in Neishabur, Iran","volume":"70","author":"Nadim A","year":"1977","journal-title":"Bull Soc Pathol Exot Filiales"},{"key":"e_1_2_5_1_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-199710000-00014"},{"key":"e_1_2_5_1_4_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200304040-00003"},{"key":"e_1_2_5_1_5_1","first-page":"30","article-title":"Nonablative fractional laser resurfacing","volume":"2","author":"Moravvej H","year":"2011","journal-title":"J Lasers Med Sci"},{"key":"e_1_2_5_1_6_1","first-page":"2271","volume-title":"Dermatology","author":"Zachary CB","year":"2012"},{"key":"e_1_2_5_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22707"},{"key":"e_1_2_5_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23092"},{"key":"e_1_2_5_1_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-016-1919-6"},{"key":"e_1_2_5_1_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199811000-00022"},{"key":"e_1_2_5_1_11_1","doi-asserted-by":"publisher","DOI":"10.12788\/j.sder.2015.0125"},{"key":"e_1_2_5_1_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-010-0801-1"},{"key":"e_1_2_5_1_13_1","first-page":"907","article-title":"Evaluation of clinical improvement in acne scars and active acne in patients treated with the 1540\u2010nm non\u2010ablative fractional laser","volume":"10","author":"Isarr\u00eda MJ","year":"2011","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_5_1_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20756"},{"key":"e_1_2_5_1_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22289"},{"key":"e_1_2_5_1_16_1","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2014.13175"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flsm.23136","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.23136","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lsm.23136","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.23136","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T16:44:01Z","timestamp":1694105041000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.23136"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,15]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1002\/lsm.23136"],"URL":"https:\/\/doi.org\/10.1002\/lsm.23136","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,15]]},"assertion":[{"value":"2019-06-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-07-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}