{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T13:31:06Z","timestamp":1789047066934,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,9,2]],"date-time":"2019-09-02T00:00:00Z","timestamp":1567382400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>On the basis of reported immediate and short\u2010term excruciating pain by patients in the post\u2010procedural period of computed tomography (CT)\u2010guided percutaneous laser disc decompression (PLDD) in our clinic, we present our initial clinical experience with a novel combi\u2010therapy using a combination of CT\u2010guided PLDD and CT\u2010guided epidural nerve blocks, which proved effective in managing the pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design\/Materials and Methods<\/jats:title><jats:p>A total of 100 patients who met the criteria for PLDD, underwent treatment for lumbar discogenic radiculopathy between 2014 and 2017. Fifty\u2010five percent of the patients were males and 45% were females with a mean age of 46.25 years. Ninety\u2010five patients underwent one level PLDD and five patients two\u2010level PLDD procedures. CT\u2010guided epidural nerve block with a combination of Bupivacaine, Lignocaine, and Kenalog was used in a 3\u00d7 procedure separated by a 1\u2010week interval. The first nerve block was given the same day, immediately after the PLDD procedure. The visual analogue scale (VAS) for pain was used during the pre\u2010procedure and post\u2010procedure periods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the patients who underwent one level PLDD, 88 had L4\u2013L5 levels, 5 had L5\u2013S1 levels and 2 had L3\u2013L4 levels. L4\u2013L5 and L5\u2013S1 levels were the most common two\u2010level PLDD locations in seven patients. Five patients in our study subsequently underwent open surgical treatment. All patients reported immediate pain relief, which was sustained after the procedure. The average pre\u2010procedure VAS score was 7.6 (range from 5 to 8.2) and the VAS score immediately after the procedure was on average 0.5 (ranging from 0 to 2).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Findings from this initial experience using a combi\u2010therapy of CT\u2010guided PLDD and CT\u2010guided epidural nerve block have shown the benefits of this novel approach, offering significant immediate pain relief in the post\u2010procedural phase, favorable outcomes in the short to mid\u2010term and a significantly reduced rate of re\u2010surgery (7%) compared with the use of only CT\u2010guided PLDD. Lasers Surg Med 00:1\u20135, 2019. \u00a9 2019 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23149","type":"journal-article","created":{"date-parts":[[2019,9,2]],"date-time":"2019-09-02T09:44:10Z","timestamp":1567417450000},"page":"419-423","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["CT\u2010Guided Percutaneous Laser Disc Decompression for Lumbar Discogenic Radiculopathy\u2010Performance of a Novel Combi\u2010Therapy"],"prefix":"10.1002","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6043-0289","authenticated-orcid":false,"given":"George","family":"Asafu Adjaye Frimpong","sequence":"first","affiliation":[{"name":"Radiology Kwame Nkrumah University of Science and Technology  PMB University Post Office, KNUST Kumasi Ghana"},{"name":"Radiology Spectra Health Imaging and Interventional Radiology Centre  P.O. Box KS 5431 Kumasi Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1168-1246","authenticated-orcid":false,"given":"Evans","family":"Aboagye","sequence":"additional","affiliation":[{"name":"Radiology Spectra Health Imaging and Interventional Radiology Centre  P.O. Box KS 5431 Kumasi Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akosua","family":"Asafu\u2010Adjaye Frimpong","sequence":"additional","affiliation":[{"name":"Radiology Spectra Health Imaging and Interventional Radiology Centre  P.O. Box KS 5431 Kumasi Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nana Esi","family":"Coleman","sequence":"additional","affiliation":[{"name":"Radiology Spectra Health Imaging and Interventional Radiology Centre  P.O. 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