{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T15:16:17Z","timestamp":1778080577573,"version":"3.51.4"},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T00:00:00Z","timestamp":1567555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007225","name":"Ministry of Science and Technology","doi-asserted-by":"publisher","award":["MOST 107\u20102314\u2010B\u2010075\u2010032\u2010MY3\u20101"],"award-info":[{"award-number":["MOST 107\u20102314\u2010B\u2010075\u2010032\u2010MY3\u20101"]}],"id":[{"id":"10.13039\/100007225","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>There have been few studies regarding the use of a picosecond\u2010domain laser for acne scars in Asians. This prospective study evaluated the efficacy and safety of a high\u2010energy 1,064\u2009nm Nd:YAG picosecond\u2010domain laser for ablation and resurfacing of facial acne scars in Asians.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Subjects were treated with a 1,064\u2009nm picosecond laser (8\u2009mm spot, 0.7\u20131.0\u2009J\/cm<jats:sup>2<\/jats:sup>, 5\u2009Hz) every 4 weeks for three sessions. Two blinded dermatologists evaluated the pre\u2010 and 3\u2010month post\u2010treatment images with a 10\u2010point improvement scale. Subject pain, global improvement, and satisfaction were also assessed. The Facial Acne Scar Quality of Life (FASQoL) questionnaire was used to evaluate the subjects\u2019 quality of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty subjects aged 18\u201350 years with Fitzpatrick skin type III\u2013V were enrolled. The median dermatologist\u2010rated improvement score was 3 out of 10. Subjects were satisfied to very satisfied with global improvement. Subjects\u2019 quality of life significantly improved with a median FASQoL score of 10 after treatment compared with 21 before treatment (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Adverse effects were limited to erythema, pain, and edema without postinflammatory hyperpigmentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The 1,064\u2009nm picosecond\u2010domain laser with ablative resurfacing parameters is safe and effective for the treatment of acne scars in Asians. Lasers Surg. Med. \u00a9 2019 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23151","type":"journal-article","created":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T11:38:19Z","timestamp":1567597099000},"page":"389-395","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Efficacy and Safety of Ablative Resurfacing With A High\u2010Energy 1,064 Nd\u2010YAG Picosecond\u2010domain Laser for the Treatment of Facial Acne Scars in Asians"],"prefix":"10.1002","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3279-4509","authenticated-orcid":false,"given":"Ying\u2010Xiu","family":"Dai","sequence":"first","affiliation":[{"name":"Department of Dermatology Taipei Veterans General Hospital Taipei 11221 Taiwan"},{"name":"Department of Dermatology, School of Medicine National Yang\u2010Ming University Taipei 11221 Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying\u2010Yen","family":"Chuang","sequence":"additional","affiliation":[{"name":"DRX Dermatology Clinic New Taipei City 24147 Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Po\u2010Yu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Taipei Veterans General Hospital Taipei 11221 Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih\u2010Chiang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Taipei Veterans General Hospital Taipei 11221 Taiwan"},{"name":"Department of Dermatology, School of Medicine National Yang\u2010Ming University Taipei 11221 Taiwan"},{"name":"Institute of Clinical Medicine National Yang\u2010Ming University Taipei 11221 Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,9,4]]},"reference":[{"key":"e_1_2_6_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsi.2017.11.001"},{"key":"e_1_2_6_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.12.043"},{"key":"e_1_2_6_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsi.2015.12.004"},{"key":"e_1_2_6_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsi.2015.07.002"},{"key":"e_1_2_6_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.06.004"},{"key":"e_1_2_6_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.09.078"},{"key":"e_1_2_6_1_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-018-0358-5"},{"key":"e_1_2_6_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.12.037"},{"key":"e_1_2_6_1_10_1","article-title":"International peeling S. 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