{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T16:24:05Z","timestamp":1790871845113,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T00:00:00Z","timestamp":1570060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Laser hair removal is the most common laser therapy and the third most commonly performed procedure with more than one million treatments in United States in 2016. This retrospective study was conducted to assess long\u2010term efficacy and safety of the 755\u2009nm laser for hair removal.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design\/Materials and Methods<\/jats:title><jats:p>Nearly, 3,606 laser treatments were performed with the long\u2010pulsed 755\u2009nm wavelength laser equipped with an epidermal cooling device between 1997 and 2005 and were followed till 2013. Standardized assessments were conducted by two treating physicians and patients at two follow\u2010up intervals. At first follow\u2010up, clearance was assessed by two physicians and clearance and satisfaction by patients. At the second follow\u2010up, patients were assessed if hair clearance sustained compared with the first follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nine hundred and forty\u2010eight patients with Fitzpatrick skin types I\u2013IV were treated with a total of 3,606 laser treatments in this study. The mean age at the beginning of the study was 35 years (\u00b111), 95.1% of patients were female (<jats:italic>n<\/jats:italic>\u2009=\u2009902) and 4.9% male (<jats:italic>n<\/jats:italic>\u2009=\u200946). Five hundred and seventy\u2010four patients received a minimum of three treatments and an average of 5.31 (3\u201316) treatments on axilla, back, bikini, breast, abdomen, face, lower extremity, or upper extremity region. First, follow\u2010up was conducted 3.9 (\u00b11.5) years after the final laser treatment. Seventy\u2010four percent of these patients received 75\u2013100% clearance as reported by the physician and 48% clearance as reported by the patient. Fifty\u2010two percent of patients reported slower hair growth and 42% change in hair texture. Ninety percent of patients treated on axilla, 82% treated on the bikini area, and 79% treated on lower extremities experienced 75% or more clearance after three treatments. Facial, as well as breast and abdomen treatments, only showed a 66% and 62%, respectively, after three treatments. For these locations, five and more treatments were needed to achieve a quote of 79% (face) or 80% (breast and abdomen) for a 75\u2013100% clearance. Upper extremity and back treatments did not have enough physician ratings to draw conclusions. Long\u2010term adverse events were minimal and were all located on the face (one patient scar, four patients herpes infection). Second follow\u2010up of 173 patients was conducted after 11.5 years (\u00b12.0) and 87.9% of patients reported that their improvement sustained.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The long\u2010pulsed 755\u2009nm alexandrite laser is a safe and efficacious treatment for the reduction of unwanted body hair with permanent results and high patient satisfaction. Lasers Surg. Med. \u00a9 2019 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23160","type":"journal-article","created":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T10:14:21Z","timestamp":1570097661000},"page":"77-83","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Evaluation of Safety and Efficacy of Laser Hair Removal With the Long\u2010Pulsed 755\u2009nm Wavelength Laser: A Two\u2010Center Study With 948 Patients"],"prefix":"10.1002","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7861-0763","authenticated-orcid":false,"given":"Elisabeth","family":"Russe","sequence":"first","affiliation":[{"name":"Center for Plastic Surgery and Lasers in Surgery and Medicine Plastische Chirurgie und Laserzentrum Innsbruck Innsbruck 6020 Austria"},{"name":"Department of Plastic and Reconstructive Surgery, Hospital of the Barmherzige Br\u00fcder Teaching Hospital of the Paracelsus Medical University Salzburg 5020 Salzburg Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Purschke","sequence":"additional","affiliation":[{"name":"Wellman Center for Photomedicine, Massachusetts General Hospital Harvard Medical School Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manfred","family":"Herold","sequence":"additional","affiliation":[{"name":"Center for Plastic Surgery and Lasers in Surgery and Medicine Plastische Chirurgie und Laserzentrum Innsbruck Innsbruck 6020 Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda H.","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Wellman Center for Photomedicine, Massachusetts General Hospital Harvard Medical School Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gottfried","family":"Wechselberger","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Hospital of the Barmherzige Br\u00fcder Teaching Hospital of the Paracelsus Medical University Salzburg 5020 Salzburg Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Russe\u2010Wilflingseder","sequence":"additional","affiliation":[{"name":"Center for Plastic Surgery and Lasers in Surgery and Medicine Plastische Chirurgie und Laserzentrum Innsbruck Innsbruck 6020 Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,10,3]]},"reference":[{"key":"e_1_2_8_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/dsu.12116"},{"key":"e_1_2_8_1_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6836297"},{"key":"e_1_2_8_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1136"},{"key":"e_1_2_8_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70181-7"},{"key":"e_1_2_8_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.asj.2005.02.003"},{"key":"e_1_2_8_1_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2000.99185.x"},{"key":"e_1_2_8_1_8_1","doi-asserted-by":"publisher","DOI":"10.1089\/clm.1997.15.225"},{"key":"e_1_2_8_1_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2000.00013.x"},{"key":"e_1_2_8_1_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2001.01073.x"},{"key":"e_1_2_8_1_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2010.01382.x"},{"key":"e_1_2_8_1_12_1","doi-asserted-by":"crossref","unstructured":"Haedersdal M G\u00f8tzsche PC. Laser and photoepilation for unwanted hair growth. The Cochrane Database of Systematic Rev 2006: Cd004684.","DOI":"10.1002\/14651858.CD004684.pub2"},{"key":"e_1_2_8_1_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.134.7.837"},{"key":"e_1_2_8_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2012.08.017"},{"key":"e_1_2_8_1_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2000.99260.x"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.23160","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lsm.23160","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.23160","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T13:01:47Z","timestamp":1694091707000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.23160"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,3]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1002\/lsm.23160"],"URL":"https:\/\/doi.org\/10.1002\/lsm.23160","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,3]]},"assertion":[{"value":"2019-08-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}