{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T01:12:19Z","timestamp":1780708339580,"version":"3.54.1"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T00:00:00Z","timestamp":1575504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>To compare the efficacy of the long\u2010pulsed Nd:YAG (1,064\u2009nm) laser versus the Q\u2010Switched Nd:YAG (1,064\u2009nm) laser in treatment of onychomycosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design\/Materials and Methods<\/jats:title><jats:p>This is a prospective cohort study. It was carried out on 20 patients with clinical and mycological evidence of onychomycosis who\u00a0were randomly assigned into two groups; group I: included 10 patients treated with biweekly sessions of long\u2010pulsed Nd:YAG (1064 nm) laser and group II; included 10 patients\u00a0treated with monthly sessions of Q\u2010Switched Nd:YAG (1064 nm) laser. The assessment was done using proximal nail measurement and\u00a0microscopic examination using 10\u201320% potassium hydroxide solution and culture on Sabouraud's dextrose agar. All patients were followed up for 6 months after the last treatment session.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fungal isolates in the present study were grouped into yeast in 50%, non\u2010dermatophyte moulds in 10%, while dermatophyte infection was detected in 40%. Each group showed a statistically significant improvement in proximal nail plate measurements with no statistically significant difference between both groups. Mycological cure was only achieved in 40% of group I and 30% of group II. Patient satisfaction was higher in group II.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Both long\u2010pulsed Nd:YAG\u00a0(1064 nm) and Q\u2010Switched Nd:YAG (1064 nm) laser systems can be used as a safe and effective modality in the treatment of onychomycosis, particularly in patients who refuse or have a contraindication to oral antifungal treatment. Lasers Surg. Med. 00:00\u201300, 2019. \u00a9 2019 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23200","type":"journal-article","created":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T10:25:53Z","timestamp":1575541553000},"page":"621-626","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Long\u2010Pulsed Nd:YAG (1,064\u2009nm) Laser Versus Q\u2010Switched Nd:YAG (1,064\u2009nm) Laser for Treatment of Onychomycosis"],"prefix":"10.1002","volume":"52","author":[{"given":"Eman H.","family":"Elmorsy","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Alexandria University Alexandria Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nouran A.","family":"Abou Khadr","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Alexandria University Alexandria Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7526-0817","authenticated-orcid":false,"given":"Alsayeda A.A.","family":"Taha","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Alexandria University Alexandria Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doaa M.","family":"Abdel Aziz","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Alexandria University Alexandria Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-0960.2002.t01-1-00570.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e32802ef47e"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(08)81272-8"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(96)90843-9"},{"key":"e_1_2_6_6_1","unstructured":"2003 Taylor & Francis Oxford UK ABR Tosti RPR Dawber E Haneke I Bristo L Thoma Onychomycosis and its treatment\u2014(pathogenesis). 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