{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T23:53:53Z","timestamp":1781308433483,"version":"3.54.1"},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,1,17]],"date-time":"2020-01-17T00:00:00Z","timestamp":1579219200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002573","name":"Yonsei University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002573","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Riehl's melanosis is a chronic acquired hyperpigmentation disorder that causes significant cosmetic problems for patients with this condition. Several treatment options, including low\u2010fluence Q\u2010switched Nd:YAG (QSNY) 1064\u2010nm laser treatment, have been attempted with inconsistent results. We aimed to investigate the beneficial effect of mid\u2010fluence QSNY 1064\u2010nm laser in the treatment of Riehl's melanosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design\/Materials and Methods<\/jats:title><jats:p>A retrospective review was conducted on patients repetitively treated with mid\u2010fluence (3.5\u20135\u2009J\/cm<jats:sup>2<\/jats:sup> with a spot size of 5\u2009mm and a pulse rate of 10\u2009Hz) QSNY 1064\u2010nm laser. Twenty\u2010one patients with Riehl's melanosis were involved. Clinical photographs, treatment parameters, and side effects were reviewed to assess the safety and efficacy of the modality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age of the patients was 57.00\u2009\u00b18.2 years, and there were 20 female patients and 1 male patient. The mean number of treatment sessions was 5.95\u2009\u00b1\u20093.6, and the mean interval between each session was 39.12\u2009\u00b1\u200913.4 days. After treatment, the mean melasma area and severity index score decreased from 12.53\u2009\u00b1\u200910.2 to 5.98\u2009\u00b1\u20095.3. At the final visit, 16 of the 21 (76.1%) patients were considered to have moderately or very much improved. No severe side effects were observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Repetitive mid\u2010fluence QSNY 1064\u2010nm laser treatment may be an effective and safe optional modality for Riehl's melanosis. Lasers Surg. Med. \u00a9 2020 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23214","type":"journal-article","created":{"date-parts":[[2020,1,17]],"date-time":"2020-01-17T10:40:20Z","timestamp":1579257620000},"page":"753-760","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Successful Treatment of Riehl's Melanosis With Mid\u2010Fluence Q\u2010Switched Nd:YAG 1064\u2010nm Laser"],"prefix":"10.1002","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9676-6681","authenticated-orcid":false,"given":"Mi Yeon","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute Yonsei University College of Medicine  211 Eonjuro Gangnam\u2010gu Seoul 06273 Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6285-2490","authenticated-orcid":false,"given":"Mi 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