{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T04:04:08Z","timestamp":1776312248763,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T00:00:00Z","timestamp":1579564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Candela Corporation","award":["device supply only"],"award-info":[{"award-number":["device supply only"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>The picosecond (PICO) laser has been a new and promising device. But, so far, there have not been many prospective studies investigating the efficacy in acne scar treatment. This study evaluated the efficacy and safety of the dual\u2010wavelength picosecond laser in the treatment of acne scar.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design\/Materials and Methods<\/jats:title><jats:p>A total of 20 patients with skin type III\u2013IV were enrolled in this study. Eighteen patients completed the study. All patients completed six treatment sessions within a 1\u2010month interval. All patients were treated using both 532 and 1,064\u2009nm fractionated dual\u2010wavelength picosecond handpieces. In evaluation, Goodman and Baron's quantitative global acne scarring grading system (GSS) was scored by two physicians. Patients also judged the results themselves by Visual Analog Scale (VAS) and pain score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average baseline score of GSS quantity and quality were 15.22 and 3.00, respectively. The final scores were 10.61 and 2.33. The average baseline of patient VAS score was 4.28. The final score was 2.00. All scores achieved statistical significance (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). No serious long\u2010term side effects were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Acne scar treatment with the fractionated dual\u2010wavelength picosecond laser has shown both efficacy and safety in this study. Lasers Surg. Med. \u00a9 2020 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23218","type":"journal-article","created":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T12:26:35Z","timestamp":1579609595000},"page":"735-742","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["A Prospective Study of Fractionated Dual\u2010Wavelength Picosecond Laser in Treating Acne Scar"],"prefix":"10.1002","volume":"52","author":[{"given":"Ching\u2010Sheng","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital and Chang Gung University College of Medicine  No. 123, Dinghu Rd., Guishan Dist. Taoyuan City 333 Taiwan"},{"name":"Department of Aesthetic Medicine Chang Gung Clinic  4F., No. 9, Ln. 130, Sec. 3, Minsheng E. Rd., Songshan Dist. Taipei City 105 Taiwan"},{"name":"Department of Cosmetic Science Chang Gung University of Science and Technology  No. 259, Wenhua 1st Rd., Guishan Dist. Taoyuan City 333 Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yau\u2010Li","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital and Chang Gung University College of Medicine  No. 123, Dinghu Rd., Guishan Dist. Taoyuan City 333 Taiwan"},{"name":"Department of Aesthetic Medicine Chang Gung Clinic  4F., No. 9, Ln. 130, Sec. 3, Minsheng E. Rd., Songshan Dist. Taipei City 105 Taiwan"},{"name":"Department of Cosmetic Science Chang Gung University of Science and Technology  No. 259, Wenhua 1st Rd., Guishan Dist. Taoyuan City 333 Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun\u2010Yu","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital and Chang Gung University College of Medicine  No. 123, Dinghu Rd., Guishan Dist. Taoyuan City 333 Taiwan"},{"name":"Department of Aesthetic Medicine Chang Gung Clinic  4F., No. 9, Ln. 130, Sec. 3, Minsheng E. Rd., Songshan Dist. Taipei City 105 Taiwan"},{"name":"Department of Cosmetic Science Chang Gung University of Science and Technology  No. 259, Wenhua 1st Rd., Guishan Dist. Taoyuan City 333 Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sindy","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital and Chang Gung University College of Medicine  No. 123, Dinghu Rd., Guishan Dist. Taoyuan City 333 Taiwan"},{"name":"Department of Aesthetic Medicine Chang Gung Clinic  4F., No. 9, Ln. 130, Sec. 3, Minsheng E. Rd., Songshan Dist. Taipei City 105 Taiwan"},{"name":"Department of Cosmetic Science Chang Gung University of Science and Technology  No. 259, Wenhua 1st Rd., Guishan Dist. Taoyuan City 333 Taiwan"},{"name":"Department of Dermatology Xiamen Chang Gung Memorial Hospital  No. 123, Xiafei Rd., Haicang Dist. Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shyue\u2010Luen","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital and Chang Gung University College of Medicine  No. 123, Dinghu Rd., Guishan Dist. Taoyuan City 333 Taiwan"},{"name":"Department of Aesthetic Medicine Chang Gung Clinic  4F., No. 9, Ln. 130, Sec. 3, Minsheng E. Rd., Songshan Dist. 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