{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T22:29:20Z","timestamp":1762900160666,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T00:00:00Z","timestamp":1625616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Treatment of vascular lesions is one of the main applications of cutaneous laser technology, while the other is laser hair removal. We present here a vascular laser pumped by a commercial hair removal laser.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design\/Materials and Methods<\/jats:title><jats:p>A novel 524\u2009nm vascular laser was designed using a 755\u2009nm hair removal laser as a pumping source. This 524\u2009nm vascular laser was used to treat facial redness and leg telangiectasias in 24 subjects. Four treatments were administered to the face at 4\u20136\u2010week intervals and final photographs were taken 8 weeks following the final treatment, while two treatments were administered to lower\u2010extremity spider veins at 2\u2010month intervals with follow\u2010up photographs 3 months following the final treatment. Blinded analysis of digital images was performed by two physicians not involved in the study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Blinded evaluation of digital photographs revealed an average improvement score of 3.3\u2009\u00b1\u20091.7 (mean\u2009\u00b1\u2009SEM) on a 0\u201310 scale for removing facial redness (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), representing a 33% improvement. Leg veins improved an average of 51% corresponding to a score of 5.1\u2009\u00b1\u20092.0 (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Side effects were mild and limited to erythema, purpura, edema, and one instance of mild hyperpigmentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This novel 524\u2009nm laser is safe and effective for treating vascularity on the face and legs, and proves the ability to create a laser platform incorporating a hair removal laser which then can be used as a pumping source for the attached vascular laser module.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23451","type":"journal-article","created":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T20:54:21Z","timestamp":1625691261000},"page":"82-88","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A laser platform incorporating a novel 524\u2009nm laser pumped by a commercial hair removal laser effectively treats facial redness and lower\u2010extremity spider veins"],"prefix":"10.1002","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8202-7893","authenticated-orcid":false,"given":"Eric F.","family":"Bernstein","sequence":"first","affiliation":[{"name":"Main Line Center for Laser Surgery  Ardmore Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jayant D.","family":"Bhawalkar","sequence":"additional","affiliation":[{"name":"Candela Inc.  Wayland Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoming","family":"Shang","sequence":"additional","affiliation":[{"name":"Candela Inc.  Wayland Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinze","family":"Qiu","sequence":"additional","affiliation":[{"name":"Candela Inc.  Wayland Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa D.","family":"Basilavecchio","sequence":"additional","affiliation":[{"name":"Main Line Center for Laser Surgery  Ardmore Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica M.","family":"Plugis","sequence":"additional","affiliation":[{"name":"Main Line Center for Laser Surgery  Ardmore Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer Y.","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Medicine SUNY Downstate Health Sciences University  Brooklyn New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James C.","family":"Hsia","sequence":"additional","affiliation":[{"name":"Candela Inc.  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