{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T12:57:16Z","timestamp":1774184236383,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,8,22]],"date-time":"2021-08-22T00:00:00Z","timestamp":1629590400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Striae distensae are atrophic dermal scars that can cause psychosocial distress among affected patients. Despite numerous available therapeutic modalities, no gold standard treatment has been established.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the long\u2010term efficacy and safety of a fractional 1064\u2010nm picosecond laser for the treatment of striae alba in individuals with dark skin types.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Twenty volunteers with Fitzpatrick skin types IV\u2013V who presented with striae alba were enrolled. Subjects were treated with a fractional 1064\u2010nm picosecond laser for four sessions at 4\u2010week\u00a0intervals. The skin texture, average melanin index (MI), and melanin variation score were assessed using Antera 3D\u00ae before treatment, at 1 month after the second treatment, and at 1, 3, and 6 months after the last treatment. Two independent investigators evaluated clinical improvement by comparing pretreatment and posttreatment photographs. The patient satisfaction rates were likewise assessed. Adverse effects were recorded during the entire study period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Significant improvement of skin texture was seen at 1 month after the final treatment (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and continuously improved until the 6\u2010month follow\u2010up visit (<jats:italic>p<\/jats:italic>\u2009=\u20090.003). The average MI significantly increased at 1 month after the final treatment (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), whereas the melanin variation score decreased throughout the follow\u2010up period. Investigator assessment at the 6\u2010month follow\u2010up revealed that 90% of subjects had moderate to marked improvement of striae appearance. Only two of 20 subjects (10%) developed transient postinflammatory hyperpigmentation (PIH) after laser treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Fractional picosecond 1064\u2010nm laser is effective and well\u2010tolerated for the treatment of striae alba in dark\u2010skinned individuals with a low incidence of PIH.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23471","type":"journal-article","created":{"date-parts":[[2021,8,22]],"date-time":"2021-08-22T11:05:40Z","timestamp":1629630340000},"page":"129-137","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Treatment of abdominal striae distensae in Fitzpatrick skin types IV to V using a 1064\u2010nm picosecond laser with a fractionated microlens array"],"prefix":"10.1002","volume":"54","author":[{"given":"Arisa","family":"Kaewkes","sequence":"first","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine 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