{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T15:32:41Z","timestamp":1785857561249,"version":"3.56.0"},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T00:00:00Z","timestamp":1679529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Microwave therapy is used to treat axillary hyperhidrosis and osmidrosis. Even while a \u201cdanger zone\u201d has been identified and reports of potential complications from nerve injury have been made, there has been little real\u2010world discussion regarding whether there is any pretreatment evaluation key factor that may lower the risk. Furthermore, the efficacy of a single treatment and the safety of high\u2010energy therapies have not been well investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study is to demonstrate the key aspects of pre\u2010therapeutic assessment, efficacy, and suitability of a single treatment, as well as the safety of high\u2010energy treatments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifteen patients with axillary hyperhidrosis\u00a0(AH) and axillary osmidrosis (AO) between ages of 20 and 50 had pretherapeutic ultrasonography and clinical assessments performed followed by a single\u2010pass microwave treatment using the miraDry system at energy level 5. The severity of AH\u00a0and\u00a0AO\u00a0was evaluated using the Hyperhidrosis Disease Severity Scale and Odor\u201010 scale, respectively, at baseline, 1 month, 3 months, and 1 year after treatment. Adverse reactions were recorded at each point of evaluation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Out of 30 treatment areas, 14 have a danger zone. Female gender, a small mid\u2010upper arm circumference, and a low body mass index\u00a0(BMI) are all associated risk factors. The average Hyperhidrosis Disease Severity Scale score decreased from 3.1\u2009\u00b1\u20090.7 to 1.3\u2009\u00b1\u20090.5 (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), while the odor\u201010 score declined from 7.1\u2009\u00b1\u20091.6 to 3.0\u2009\u00b1\u20091.6 (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), indicating a significant improvement in AH and AO. Most of the unfavorable treatment effects disappeared within the first month.<\/jats:p><\/jats:sec><jats:sec><jats:title>Limitations<\/jats:title><jats:p>This study has no objective quantitative measurement of axillary odor severity and sweat assessment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Female patients, those with a smaller mid\u2013upper arm circumference, and those with a low BMI should be treated with extra caution, and the tumescent anesthetic dose may be increased based on safety. A high\u2010energy microwave treatment procedure performed in a single session is a safe and effective therapeutic option with good recovery.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23656","type":"journal-article","created":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T07:44:02Z","timestamp":1679557442000},"page":"372-377","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["A single session of high\u2010energy microwave axillary hyperhidrosis and osmidrosis therapy: Key pretherapeutic assessment and outcome analysis"],"prefix":"10.1002","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3355-171X","authenticated-orcid":false,"given":"Yu\u2010Hsin","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital and Chang Gung University College of Medicine Taoyuan Taiwan"},{"name":"Department of Dermatology Chang Gung Memorial Hospital Linkou and Taipei Taiwan"},{"name":"Department of Aesthetic Medicine Chang Gung Memorial Hospital Taoyuan Taiwan"},{"name":"Department of Aesthetic Medicine Chang Gung Clinic Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun\u2010Yu","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital and Chang Gung University College of Medicine Taoyuan Taiwan"},{"name":"Department of Aesthetic Medicine Chang Gung Memorial Hospital Taoyuan Taiwan"},{"name":"Department of Aesthetic Medicine Chang Gung Clinic Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyue\u2010Luen","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital and Chang Gung University College of Medicine Taoyuan Taiwan"},{"name":"Department of Aesthetic Medicine Chang Gung Memorial Hospital Taoyuan Taiwan"},{"name":"Department of Aesthetic Medicine Chang Gung Clinic Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sindy","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital and Chang Gung University College of Medicine Taoyuan Taiwan"},{"name":"Department of Aesthetic Medicine Chang Gung Memorial Hospital Taoyuan Taiwan"},{"name":"Department of Aesthetic Medicine Chang Gung Clinic Taipei Taiwan"},{"name":"Department of Dermatology Xiamen Chang Gung Memorial Hospital Xiamen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yau\u2010Li","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital and Chang Gung University College of Medicine Taoyuan Taiwan"},{"name":"Department of Aesthetic Medicine Chang Gung Memorial Hospital Taoyuan Taiwan"},{"name":"Department of Aesthetic Medicine Chang Gung Clinic Taipei 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