{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:24:01Z","timestamp":1771467841144,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,4,23]],"date-time":"2023-04-23T00:00:00Z","timestamp":1682208000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the efficacy and safety of a 1927\u2010nm fractional thulium fiber laser treatment for Becker's nevus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis of patients with Becker's nevus who were treated with a 1927\u2010nm fractional thulium fiber laser was conducted. Grading for lightening was set quarterly by physician global assessment of the pre\u2010 and postphotographs (I: &lt;25%; II: 25%\u201350%; III: 51%\u201375%; and IV: &gt;75% for marked lightening). Grading validation was exercised using intra\u2010 and interobserver agreement analysis among 10 dermatologists to determine the percent of agreement and the intraclass correlation coefficient. Grades I and II were classified as treatment failure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 21 patients were recruited for analysis. The average number of treatment sessions was 2.1 per patient. A total of 13 patients achieved successful outcomes (grades III and IV) while 8 patients experienced treatment failure (grades I and II). Partial recurrence and transient hypopigmentation on adjacent skin were the main adverse effects. Only one patient reported worsening of the nevus. Overall agreement among the raters for the outcomes was graded from \u201cvery good\u201d to \u201cexcellent,\u201d and the intraclass correlation coefficient, kappa, was 0.8.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A 1927\u2010nm fractional thulium fiber laser may be effective to ameliorate the pigment of Becker's nevus and achieve acceptable cosmetic outcomes. However, further studies are required in this area to improve and optimize the results.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23670","type":"journal-article","created":{"date-parts":[[2023,4,23]],"date-time":"2023-04-23T10:48:11Z","timestamp":1682246891000},"page":"547-554","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Efficacy of non\u2010ablative 1927\u2010nm fractional thulium fiber laser for the treatment of Becker's nevus: Intra\u2010 and interobserver agreement study"],"prefix":"10.1002","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4671-010X","authenticated-orcid":false,"given":"Abdulmajeed","family":"Alajlan","sequence":"first","affiliation":[{"name":"Department of Dermatology, College of Medicine King Saud University Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4467-9425","authenticated-orcid":false,"given":"Sami","family":"Alsuwaidan","sequence":"additional","affiliation":[{"name":"Department of Dermatology, College of Medicine King Saud University Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,4,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1949.01530020023005"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-019-02734-3"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2017.04.003"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-015-0123-y"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2016.28.6.697"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13273"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1998.tb04298.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.12.1488"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/14764172.2017.1326613"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2011.01971.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/14764172.2018.1493513"},{"issue":"11","key":"e_1_2_6_13_1","first-page":"1317","article-title":"Nonablative 1927 nm fractional resurfacing for the treatment of facial photopigmentation","volume":"13","author":"Brauer JA","year":"2014","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/001316446002000104"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/001316447303300309"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/14764172.2015.1114647"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.05.033"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22465"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23599"},{"issue":"3","key":"e_1_2_6_20_1","first-page":"14","article-title":"Efficacy and safety of short\u2010pulse erbium: yttrium aluminum garnet laser treatment of Becker's nevus in Saudi patients: a pilot study","volume":"11","author":"Al\u2010Saif F","year":"2017","journal-title":"Int J Health Sci"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.3109\/14764172.2013.854121"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.23670","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,16]],"date-time":"2023-08-16T21:24:28Z","timestamp":1692221068000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.23670"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,23]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1002\/lsm.23670"],"URL":"https:\/\/doi.org\/10.1002\/lsm.23670","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,23]]},"assertion":[{"value":"2022-11-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}