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The consensus of the protocols and parameters based upon the published clinical trials of their application to the vaginal and urologic conditions associated with genitourinary syndrome of menopause was developed and organized according to device and condition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The status of FDA clearances and future pathways are discussed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This consensus article categorizes and presents the protocols and practices for the main classes of lasers and energy\u2010based devices for genitourinary applications in future clinical trials.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23672","type":"journal-article","created":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T21:42:02Z","timestamp":1683063722000},"page":"444-454","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Light and energy\u2010based therapeutics for genitourinary applications: Consensus on protocols and best practices"],"prefix":"10.1002","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9720-9537","authenticated-orcid":false,"given":"Macrene R.","family":"Alexiades","sequence":"first","affiliation":[{"name":"Dermatology &amp; Laser Surgery Center of New York New York New York USA"},{"name":"Yale University School of Medicine New Haven Connecticut USA"},{"name":"Syggros Hospital Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheryl","family":"Iglesias","sequence":"additional","affiliation":[{"name":"Departments of Obstetrics and Gynecology and Urology Georgetown University School of Medicine Washington District of Columbia USA"},{"name":"MedStar Health Washington District of Columbia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Sokol","sequence":"additional","affiliation":[{"name":"Medicine and Reconstructive Surgery Stanford University School of Medicine Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8852-9010","authenticated-orcid":false,"given":"Adrian","family":"Gaspar","sequence":"additional","affiliation":[{"name":"Gynecology Department Uroclinic Mendoza University of Mendoza Argentina  Mendoza Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yona","family":"Tadir","sequence":"additional","affiliation":[{"name":"Beckman Laser Institute and Medical Clinic University of California Irvine USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22637"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23031"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.01.003"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20667"},{"issue":"11","key":"e_1_2_6_6_1","first-page":"1088","article-title":"High intensity focused electromagnetic field (HIFEM) devices in dermatology","volume":"18","author":"Alexiades M","year":"2019","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_6_7_1","first-page":"371","article-title":"Carbon dioxide laser in gynecology","volume":"6","author":"Bellina JH","year":"1977","journal-title":"Obstet Gynecol Annu"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0039-6109(16)41442-8"},{"key":"e_1_2_6_9_1","first-page":"711","article-title":"Carbon dioxide laser treatment for condylomata acuminata venereal infections","volume":"55","author":"Baggish MS","year":"1980","journal-title":"Obstet Gynecol"},{"issue":"2","key":"e_1_2_6_10_1","first-page":"147","article-title":"Colposcopy and the CO2 laser for treatment of cervical intraepithelial neoplasia. 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