{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T02:17:00Z","timestamp":1740104220061,"version":"3.37.3"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,1,21]],"date-time":"2024-01-21T00:00:00Z","timestamp":1705795200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Fractional radiofrequency devices have been demonstrated to improve skin texture, such as smoothness, rhytides, brightness, and atrophic acne scars, by increasing dermal thickness, dermal collagen content, and dermal fibrillin content. The objective of the study is to assess the efficacy and adverse effects of this device on Asian patients of skin type III and IV with skin textural changes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>The study was designed as a prospective, open\u2010labeled single\u2010arm study, which was conducted with 20 Chinese patients aged 21\u201360 years and having irregularities in their skin texture, rhytides, and acne scars. The patients received six treatments at intervals of 4 weeks. Treatment was initiated with the maximum energy tolerated, which was then adjusted during the course of treatment if the patients felt excessive discomfort. A total of two passes were delivered in each session. Physician assessment results and standardized photographs were collected at the baseline, after all treatment visits, and at 1, 2, and 6 months after the final treatment visit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 17 patients completed the study according to the established protocol. At the 6\u2010month follow\u2010up, 71% of patients were satisfied and 24% of patients were very satisfied with the received treatments, and the treatment physician reported varying degrees of improvement based on the global assessment scale in 60% of the subjects. While the anticipated side effects, such as erythema, edema, pinpoint bleeding, scab formation, and flare of acne, were noted in the patients, no serious adverse effects occurred.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The use of fractional radiofrequency improves skin texture and is safe for use in Asian patients of skin type III and IV. No long\u2010term serious adverse effects were noted.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23752","type":"journal-article","created":{"date-parts":[[2024,1,22]],"date-time":"2024-01-22T05:14:34Z","timestamp":1705900474000},"page":"142-149","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The use of fractional radiofrequency in Asian patients to improve skin texture"],"prefix":"10.1002","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6041-4876","authenticated-orcid":false,"given":"Mandy W. M.","family":"Chan","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Dermatology The University of Hong Kong Hong\u00a0Kong SAR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnes W. S.","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Medicine &amp; Therapeutics, Faculty of Medicine The Chinese University of Hong Kong Hong Kong SAR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4603-6407","authenticated-orcid":false,"given":"Christina S. M.","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Dermatology The University of Hong Kong Hong\u00a0Kong SAR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samantha Y. N.","family":"Shek","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Dermatology The University of Hong Kong Hong\u00a0Kong SAR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi Keung","family":"Yeung","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Dermatology The University of Hong Kong Hong\u00a0Kong SAR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taro","family":"Kono","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Tokai University Isehara Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9657-1435","authenticated-orcid":false,"given":"Henry H. 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