{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T06:33:32Z","timestamp":1788417212847,"version":"build-2803163510"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,2,14]],"date-time":"2024-02-14T00:00:00Z","timestamp":1707868800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2024,3]]},"abstract":"Abstract<\/jats:title>\n \n Objectives<\/jats:title>\n Ablative fractional lasers have long been considered the gold standard for facial resurfacing for advanced photoaging. These lasers offer an improved safety profile compared to traditional ablative lasers but typically require more treatment sessions given their fractional approach. In this study, we evaluate a new novel 2910\u2009nm erbium\u2010doped fluoride glass fiber laser (2910\u2009nm fiber laser) (UltraClear; Acclaro Medical) for full\u2010face and neck resurfacing for the treatment of advanced photoaging.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Twenty\u2010two healthy subjects aged 44\u201380 years presenting for advanced facial photoaging and rhytides were enrolled in the study. All subjects received three full\u2010face and neck, multipass treatments utilizing the 2910\u2009nm fiber laser spaced 6\u20138 weeks apart. Subjects were asked to rate the average level of pain during the treatment. At 90 days following subjects' third treatment subjects evaluated their improvement using a Global Aesthetic Improvement Scale (GAIS) and rated their satisfaction with the treatment. Evaluation of pretreatment and posttreatment photos was completed by two blinded physician reviewers. Reviewers were asked to identify the pretreatment and posttreatment photographs and to rate the degree of improvement utilizing a GAIS.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Fifteen participants completed the study; six were exited from the study (withdrew or lost to follow\u2010up). The average subject GAIS score for overall appearance was 3.8. The average subject satisfaction level at follow\u2010up was 4.8. The average subject pain score was 4.9. One blinded physician reviewer correctly identified 100% of subjects' posttreatment photographs, while the second blinded reviewer correctly identified 93%. Blinded evaluation of digital photographs revealed an average GAIS score of 3.2. Posttreatment skin responses included pin\u2010point hemorrhage, erythema, edema, and soft tissue crusting lasting 5\u20137 days. There were no instances of infection, scarring or hypopigmentation. There were two instances of temporary hyperpigmentation.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Treatment with the novel 2910\u2009nm fiber laser is safe and effective in treating advanced photoaging and rhytides. Three treatments produced moderate to marked improvement with high patient satisfaction and treatment was associated with less discomfort and downtime compared to conventional fractional ablative lasers.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/lsm.23764","type":"journal-article","created":{"date-parts":[[2024,2,14]],"date-time":"2024-02-14T07:39:47Z","timestamp":1707896387000},"page":"249-256","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Full\u2010face and neck resurfacing with a novel ablative fractional 2910\u2009nm erbium\u2010doped fluoride glass fiber laser for advanced photoaging"],"prefix":"10.1002","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6921-0028","authenticated-orcid":false,"given":"Taryn N.","family":"Murray","sequence":"first","affiliation":[{"name":"Dermatology and Laser Surgery Center Houston Texas USA"},{"name":"Dermatology & Plastic Surgery Institute Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7377-0271","authenticated-orcid":false,"given":"Jamie K.","family":"Hu","sequence":"additional","affiliation":[{"name":"Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery University of Miami Miller School of Medicine Miami Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul M.","family":"Friedman","sequence":"additional","affiliation":[{"name":"Dermatology and Laser Surgery Center Houston Texas USA"},{"name":"Department of Dermatology, McGovern Medical School University of Texas MD Anderson Cancer Center Houston Texas USA"},{"name":"Department of Dermatology, Weill Cornell Medical College Houston Methodist Hospital Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,14]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"53","article-title":"Complications of carbon dioxide laser resurfacing: an evaluation of 500 patients","volume":"20","author":"Nanni CA","year":"1997","journal-title":"Lasers Surg Med"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2001.01015.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9101(2000)26:2<208::AID-LSM12>3.0.CO;2-R"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.135.4.444"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20048"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S77996"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20310"},{"key":"e_1_2_8_9_1","volume-title":"Ablative laser resurfacing","author":"Verma N","year":"2023"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23624"},{"key":"e_1_2_8_11_1","first-page":"3","article-title":"The 1440\u2009nm and 1927\u2009nm nonablative fractional diode laser: current trends and future directions","volume":"19","author":"Friedman PM","year":"2020","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000003321"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.10870.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900090403"},{"key":"e_1_2_8_15_1","unstructured":"WalshJT HruzaGJ FlotteTF DeutschTF ManniJG. Moul\u2010ton PF: comparison of tissue ablation using TEA COz and Er:YAG lasers. Optical Society of America Washington DC Technical Digest Conference on Lasers and Electro\u2010optics.1987. (pp. 88)."}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.23764","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,23]],"date-time":"2024-04-23T23:19:46Z","timestamp":1713914386000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.23764"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,14]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["10.1002\/lsm.23764"],"URL":"https:\/\/doi.org\/10.1002\/lsm.23764","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,14]]},"assertion":[{"value":"2023-08-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}