{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T01:49:57Z","timestamp":1777513797935,"version":"3.51.4"},"reference-count":7,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T00:00:00Z","timestamp":1715126400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>There remains an unmet need for a laser\u2010enabled tissue coring device that can effectively improve face and neck skin laxity and rhytides. We investigate a novel 2910\u2009nm erbium\u2010doped fluoride glass fiber laser (2910\u2009nm fiber laser) (UltraClear; Acclaro Medical) for laser\u2010coring of submental tissue.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Five subjects, Glogau scale III\u2212IV, were treated with a single pulse of the laser\u2010coring mode of the 2910\u2009nm fiber laser in the submentum. A 4\u2009mm punch biopsy was immediately performed. Biopsy specimens were sectioned and stained with hematoxylin and eosin and placed on glass slides. All sections were reviewed, and sections containing the center of the transected core were analyzed for depth and diameter of the ablative microchannel and width of the surrounding zone of coagulation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 15 intact micro\u2010cores were analyzed. Histological analysis revealed an average\u2009\u00b1\u2009standard deviation microchannel diameter of 242.5\u2009\u00b1\u200965.2\u2009\u00b5m, an average ablative depth of 980\u2009\u00b1\u2009318.8\u2009\u00b5m, and an average zone of coagulation of 104\u2009\u00b1\u200932\u2009\u00b5m.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Laser\u2010enabled tissue coring with a novel 2910\u2009nm fiber laser can safely achieve a wider microchannel diameter with ablative depth extending to the mid and deep dermis, which has the potential for collagen contraction and tissue tightening. Laser\u2010coring to this ablation diameter and depth and with the surrounding zone of coagulation was found to be safe without adverse effects of post\u2010inflammatory erythema or scarring in our study.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23792","type":"journal-article","created":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T09:14:20Z","timestamp":1715159660000},"page":"462-465","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Histological analysis of laser\u2010enabled tissue coring with a novel 2910\u2009nm erbium\u2010doped fluoride glass fiber laser"],"prefix":"10.1002","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6921-0028","authenticated-orcid":false,"given":"Taryn N.","family":"Murray","sequence":"first","affiliation":[{"name":"Dermatology &amp; Plastic Surgery Institute Cleveland Clinic Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasina","family":"Maredia","sequence":"additional","affiliation":[{"name":"Department of Dermatology Mayo Clinic Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul M.","family":"Friedman","sequence":"additional","affiliation":[{"name":"Dermatoloy &amp; Laser Surgery Center Houston Texas USA"},{"name":"Department of Dermatology, McGovern Medical School University of Texas MD Anderson Cancer Center Houston Texas USA"},{"name":"Department of Dermatology, Weill Cornell Medical College Houston Methodist Hospital Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,5,8]]},"reference":[{"issue":"11","key":"e_1_2_7_2_1","first-page":"1274","article-title":"Fractional laser skin resurfacing","volume":"11","author":"Alexiades\u2010Armenakas MR","year":"2012","journal-title":"J Drugs Dermatol: JDD"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2008.34413.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000003905"},{"key":"e_1_2_7_5_1","first-page":"72","article-title":"A first look at rotational fractional resection","volume":"12","author":"Sundaram H","year":"2018","journal-title":"Pract Dermatol"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23059"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000004547"},{"issue":"11","key":"e_1_2_7_8_1","first-page":"1245","article-title":"Analysis of depth of ablation, thermal damage, wound healing, and wound contraction with erbium YAG laser in a yorkshire pig model","volume":"14","author":"Alsaad SM","year":"2015","journal-title":"J Drug Dermatol: JDD"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.23792","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,16]],"date-time":"2024-06-16T04:45:22Z","timestamp":1718513122000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.23792"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,8]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1002\/lsm.23792"],"URL":"https:\/\/doi.org\/10.1002\/lsm.23792","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,8]]},"assertion":[{"value":"2024-01-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}