{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T21:17:38Z","timestamp":1771363058595,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T00:00:00Z","timestamp":1718668800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Freckles and lentigines are common pigmented problems which not only cause substantial cosmetic morbidity but also create psychosocial concern. The available modalities for the treatment of pigmented lesions are often unsatisfactory for patients, require a long treatment period, and often cause skin irritation. With the advent of lasers, safe and effective treatment options for epidermal pigmentation have become more varied for different Fitzpatrick skin types. We aimed to evaluate the efficacy and safety of 577\u2010nm yellow laser in the treatment of pigmented epidermal lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study was carried out on 50 patients presented with pigmented epidermal lesions (25 presented with freckles and 25 presented with lentigines). Each patient received four treatment sessions with a 577\u2010nm diode laser at 2\u2010week intervals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was significant improvement in freckles and lentigines, as 23 out of 50 patients showed marked improvement, 11 patients showed moderate improvement, 10 patients showed mild improvement, and only six patients had no changes. Moreover, 23 patients were very satisfied, 18 patients were satisfied, and nine patients were not satisfied. As regards the safety of the 577\u2010nm yellow laser, there was no significant adverse effect among patients except pain, erythema, and hyperpigmentation, which resolved within one month after treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study showed that the 577\u2010nm yellow laser is an effective, safe, and well\u2010tolerated device in the treatment of freckles and lentigines.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23814","type":"journal-article","created":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T04:35:33Z","timestamp":1718771733000},"page":"551-556","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Efficacy and Safety of 577\u2010nm Yellow Laser in the Treatment of Pigmented Epidermal Lesions"],"prefix":"10.1002","volume":"56","author":[{"given":"Essamelden M.","family":"Mohamed","sequence":"first","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Al\u2010Azhar University Assiut Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hazem L.","family":"Abd Elaleem","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Al\u2010Azhar University Assiut Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona A. H.","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Al\u2010Azhar University Assiut Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6212-9748","authenticated-orcid":false,"given":"Mahmoud A.","family":"Rageh","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Al\u2010Azhar University Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,18]]},"reference":[{"key":"e_1_2_11_2_1","first-page":"145","article-title":"Current Evidence and Applications of Photodynamic Therapy in Dermatology","volume":"7","author":"Wan M. 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