{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T02:16:43Z","timestamp":1740104203393,"version":"3.37.3"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T00:00:00Z","timestamp":1720656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to assess the value of CO<jats:sub>2<\/jats:sub> laser vaporization in treating huge adult laryngeal vascular anomalies (HALVAs) by combining it with bleomycin injection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>This study retrospectively reviewed the records of 13 adult patients who underwent 18 different procedures. Methods to treat\u00a0HALVAs include traditional bleomycin injection\u00a0and CO<jats:sub>2<\/jats:sub> laser vaporization combined with bleomycin injection between September 2009 and\u00a0January 2023. Treatment results were evaluated\u00a0by the grade of lumen constriction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of five males and eight females, with an average age of 46.3 years (range, 22\u201366 years), were included in the study. The huge adult laryngeal vascular anomalies in our study were greater than 1633.71\u2009mm<jats:sup>3<\/jats:sup>, and the long diameters of the bases were longer than 15\u2009mm. Compared with the bleomycin injection\u2010only group, the results with the CO<jats:sub>2<\/jats:sub> laser vaporization and bleomycin injection combined were better.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Both bleomycin injection and CO<jats:sub>2<\/jats:sub> laser vaporization are safe treatment methods. Their combination may produce better results for huge adult laryngeal vascular anomalies.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.23824","type":"journal-article","created":{"date-parts":[[2024,7,12]],"date-time":"2024-07-12T04:38:51Z","timestamp":1720759131000},"page":"657-663","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Combined CO<sub>2<\/sub> Laser Vaporization and Bleomycin Injection to Treat Huge Adult Laryngeal Vascular Anomalies: Innovative Application of CO<sub>2<\/sub> Laser in Otolaryngology"],"prefix":"10.1002","volume":"56","author":[{"given":"Xiufa","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery, Eye, Ear, Nose &amp; Throat Hospital Fudan University shanghai People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Departments of Laser Plastic Surgery, Eye, Ear, Nose &amp; Throat Hospital Fudan University Shanghai People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery, Eye, Ear, Nose &amp; Throat Hospital Fudan University shanghai People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9466-1146","authenticated-orcid":false,"given":"Chunsheng","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery, Eye, Ear, Nose &amp; Throat Hospital Fudan University shanghai People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,11]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1089\/pho.2011.3058"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21919"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016489.2017.1419577"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/14764172.2011.606465"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-991182"},{"key":"e_1_2_9_7_1","first-page":"25","article-title":"Genital Warts: A Comprehensive Review","volume":"5","author":"Yanofsky V. R.","year":"2012","journal-title":"The Journal of Clinical and Aesthetic Dermatology"},{"issue":"8","key":"e_1_2_9_8_1","first-page":"699","article-title":"Port\u2010Wine Stain Nodules in the Adult: Report of 20 Cases Treated by CO2 Laser Vaporization","volume":"27","author":"Pozo J.","year":"2001","journal-title":"Dermatologic Surgery"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2014.06.016"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2009.02.011"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9101(1998)23:4<221::AID-LSM5>3.0.CO;2-A"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-005-1557-9"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-010-1967-1"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-005-0057-1"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0027-5107(90)90110-P"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-003-1058-6"},{"key":"e_1_2_9_17_1","first-page":"1477","article-title":"Comparison of KTP, Thulium, and CO2 Laser in Stapedotomy Using Specialized Visualization Techniques: Thermal Effects","volume":"271","author":"Kamalski D. M.","year":"2014","journal-title":"European Archives of Otorhinolaryngology"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20567"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17228665"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13816"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2018.08.001"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.23824","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T19:42:07Z","timestamp":1724355727000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.23824"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,11]]},"references-count":20,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1002\/lsm.23824"],"URL":"https:\/\/doi.org\/10.1002\/lsm.23824","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"type":"print","value":"0196-8092"},{"type":"electronic","value":"1096-9101"}],"subject":[],"published":{"date-parts":[[2024,7,11]]},"assertion":[{"value":"2024-03-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}