{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:50:03Z","timestamp":1786978203026,"version":"build-2736575974"},"reference-count":31,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,9,22]],"date-time":"2024-09-22T00:00:00Z","timestamp":1726963200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Acne scarring results from the inflammation associated with acne papules, which alters dermal collagen, typically producing depressed scars. Lasers have been used to remodel skin improving the texture and appearance of acne scars. Herein, we investigate a new 2910\u2009nm, erbium\u2010doped, fluoride glass, fiber laser for improving acne scars. This novel laser delivers up to 5000\u2009Hz low\u2010energy pulses, providing a unique treatment modality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Fourteen subjects with rolling and\/or boxcar acne scars were enrolled in this study. Thirteen subjects completed the final visit and received three treatments with the 2910\u2009nm fiber laser at 6\u20138\u2010week intervals. Eight subjects were Fitzpatrick type II and five were Fitzpatrick type III. Digital images were taken pre\u2010 and 1\u2010 and 3\u2010months posttreatment and evaluated by two blinded reviewers in a randomized fashion for improvement. Subjects and the treating physician completed a Global Aesthetic Improvement Scale (GAIS) before treatment and at each visit to subjectively evaluate treatment effect. Histological analysis was performed on ex vivo lower eyelid skin samples. Side effects were evaluated by the treating physician and included erythema, edema, and pinpoint bleeding.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Evaluation of blinded digital images revealed a mean improvement of 47.3%\u2009\u00b1\u200914.2% (mean\u2009\u00b1\u2009SEM) 3 months following the final treatment. GAIS scores demonstrated improvement as evaluated by both the subjects and the treating physician. Side effects averaged trace\u2010to\u2010mild erythema, edema, and pinpoint bleeding.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study shows that the 2910\u2009nm, erbium\u2010doped, fluoride glass, fiber laser is safe and effective for improving the appearance of acne scars.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lsm.23845","type":"journal-article","created":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T01:56:23Z","timestamp":1727056583000},"page":"755-761","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The 2910\u2010nm Fiber Laser Is Safe and Effective for Improving Acne Scarring"],"prefix":"10.1002","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8202-7893","authenticated-orcid":false,"given":"Eric","family":"Bernstein","sequence":"first","affiliation":[{"name":"Main Line Center for Laser Surgery Ardmore Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Alajmi","sequence":"additional","affiliation":[{"name":"Main Line Center for Laser Surgery Ardmore Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Wang","sequence":"additional","affiliation":[{"name":"State University of New York Downstate Health Sciences University Brooklyn New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Hochman","sequence":"additional","affiliation":[{"name":"Medstar Georgetown University Hospital Washington District of Columbia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Biesman","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James F.","family":"Sanzo","sequence":"additional","affiliation":[{"name":"Orefield Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,22]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1996.tb00497.x"},{"key":"e_1_2_5_2_2","unstructured":"discussion4\u20105."},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22410"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2014.3045"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000004111"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1997.tb00677.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20974"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20659"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2010.01513.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsc.2011.05.005"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2011.02050.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1097\/00042728-200810000-00004","article-title":"Second\u2010Generation 1550\u2010nm Fractional Photothermolysis for the Treatment of Acne Scars","volume":"34","author":"Chrastil B.","year":"2008","journal-title":"Dermatologic Surgery"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16643"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-010-0801-1"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000000640"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-021-03465-0"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22734"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23151"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2011.02267.x"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2007.33059.x"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S392459"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23764"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23729"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23624"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23714"},{"key":"e_1_2_5_26_1","first-page":"551","article-title":"Treatment of Atrophic Facial Acne Scars With a Dual\u2010Mode Er:YAG Laser","volume":"28","author":"Tanzi E. 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