{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T13:10:06Z","timestamp":1749647406708,"version":"3.41.0"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T00:00:00Z","timestamp":1744934400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to evaluate the efficacy and safety of transcutaneous temperature\u2010controlled radiofrequency (TTCRF) in the treatment of female vulvar lichen sclerosus (VLS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis was conducted on VLS patients treated with TTCRF at our hospital between May 2021 and May 2023. Each patient underwent ten TTCRF sessions, spaced 1 week apart. Complications were monitored throughout the treatment, and efficacy was assessed using the Cattaneo scoring system and the Patient Global Impression of Change (PGI\u2010C) questionnaire at 1 and 6 months Posttreatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 40 patients were included in the study, with a mean age of 44.98\u2009\u00b1\u200911.14 years and a mean BMI of 22.78\u2009\u00b1\u20092.62\u2009kg\/m\u00b2. Follow\u2010up results at 1 and 6 months Posttreatment showed significant improvements in pruritus degree, skin elasticity, and skin color compared to baseline (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05), although no significant change in lesion scope was observed. According to the PGI\u2010C questionnaire, 75% (30\/40) of patients reported improvement or significant improvement at 1 month Posttreatment, which decreased to 60% (24\/40) at 6 months. No adverse reactions were reported during the treatment or follow\u2010up periods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>TTCRF is an effective and safe treatment for female VLS, offering significant short\u2010term symptom relief. However, further research is needed to confirm long\u2010term benefits.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lsm.70016","type":"journal-article","created":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T17:33:26Z","timestamp":1744997606000},"page":"383-388","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Outcomes of Temperature\u2010Controlled Radiofrequency in Treating Vulvar Lichen Sclerosus: A Pilot Study"],"prefix":"10.1002","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6724-2125","authenticated-orcid":false,"given":"Nengxiu","family":"Wu","sequence":"first","affiliation":[{"name":"Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics &amp; Gynecology and Pediatrics, Fujian Medical University Fuzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Li","sequence":"additional","affiliation":[{"name":"Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics &amp; Gynecology and Pediatrics, Fujian Medical University Fuzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4631-0218","authenticated-orcid":false,"given":"Chaoqin","family":"Lin","sequence":"additional","affiliation":[{"name":"Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics &amp; Gynecology and Pediatrics, Fujian Medical University Fuzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,18]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJWH.S191200"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/jmh.JMH_13_17"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003944"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14096"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2015.0643"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23506"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina58020181"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16066"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/asj\/sjab174"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09997.x"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13136"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000001453"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-022-03180-5"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2022.919135"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/7480754"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.05.006"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2016.06.019"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/13697137.2021.1948004"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sxmr.2021.03.006"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18137153"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-023-07055-z"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/asj\/sjy180"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.16251"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22450"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.70016","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T12:52:43Z","timestamp":1749646363000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.70016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,18]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1002\/lsm.70016"],"URL":"https:\/\/doi.org\/10.1002\/lsm.70016","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"type":"print","value":"0196-8092"},{"type":"electronic","value":"1096-9101"}],"subject":[],"published":{"date-parts":[[2025,4,18]]},"assertion":[{"value":"2025-03-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}