{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T16:40:03Z","timestamp":1772988003394,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T00:00:00Z","timestamp":1767139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T00:00:00Z","timestamp":1767139200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To objectively quantify early and mid\u2010term facial tightening after dual\u2010wavelength Er:YAG\/Nd:YAG laser treatment in Chinese women using three\u2010dimensional (3D) imaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>In this prospective observational study, 13 women with lower facial aging underwent four full\u2010face treatment sessions of dual\u2010wavelength Er:YAG\/Nd:YAG (Fotona 4D) at 1\u2010month intervals. Standardized 3D facial images were obtained at baseline and at 1 week, 1, 3, and 6 months after completion of the final treatment session. The primary objective outcomes were vertical displacements (mm) of predefined periocular and midfacial landmarks relative to baseline. Secondary outcomes included Wrinkle Severity Rating Scale (WSRS) scores for nasolabial folds and VISIA pore scores, evaluated at baseline and at 3 and 6 months. Adverse events were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      3D analysis demonstrated significant early and mid\u2010term tightening in the lateral periorbital region. The vertical distance from the lateral canthus to the nasal base decreased by approximately 0.50\u20130.63\u2009mm at 1 week and by 0.60\u20130.63\u2009mm at 3 months bilaterally (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), with partial rebound but persistence of mild improvement at 6 months. The highest point of the zygomatic bone showed a delayed, mild elevation that peaked around 1\u20133 months. WSRS scores for nasolabial folds decreased by about 1 grade at 3 and 6 months on both sides (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). VISIA pore scores improved from 4.97\u2009\u00b1\u20090.36 at baseline to 3.37\u2009\u00b1\u20090.43 at 3 months and 3.73\u2009\u00b1\u20090.54 at 6 months (both\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Only transient erythema and edema were observed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Dual\u2010wavelength Er:YAG\/Nd:YAG laser tightening produced early and mid\u2010term improvements in periocular and midfacial laxity, as captured by 3D landmark displacement, with concomitant improvements in wrinkles and pores. 3D imaging provides a sensitive, objective tool to visualize region\u2010specific dynamic responses to energy\u2010based facial rejuvenation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lsm.70095","type":"journal-article","created":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T08:14:35Z","timestamp":1767168875000},"page":"113-119","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Three\u2010Dimensional Imaging of Dynamic Changes After Nd:YAG\/Er:YAG Laser Skin Tightening: A Prospective Study"],"prefix":"10.1002","volume":"58","author":[{"given":"Jun","family":"Qi","sequence":"first","affiliation":[{"name":"Laser Aesthetic Center, Plastic Surgery Hospital Peking Union Medical College and Chinese Academy of Medical Sciences Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qixuan","family":"Wang","sequence":"additional","affiliation":[{"name":"Laser Aesthetic Center, Plastic Surgery Hospital Peking Union Medical College and Chinese Academy of Medical Sciences Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lvping","family":"Huang","sequence":"additional","affiliation":[{"name":"Laser Aesthetic Center, Plastic Surgery Hospital Peking Union Medical College and Chinese Academy of Medical Sciences Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Zhang","sequence":"additional","affiliation":[{"name":"Laser Aesthetic Center, Plastic Surgery Hospital Peking Union Medical College and Chinese Academy of Medical Sciences Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,31]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3182362b96"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000279348.09156.c3"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-012-9904-3"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.55625"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.06.039"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-023-01078-9"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-021-02682-w"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/srt.12135"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.14023"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/14764172.2018.1439964"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/srt.12816"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.70095","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lsm.70095","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.70095","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T11:14:39Z","timestamp":1772968479000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.70095"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,31]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1002\/lsm.70095"],"URL":"https:\/\/doi.org\/10.1002\/lsm.70095","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,31]]},"assertion":[{"value":"2025-10-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}