{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T05:53:44Z","timestamp":1781589224272,"version":"3.54.5"},"reference-count":12,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Importance<\/jats:title>\n                    <jats:p>Acquired digital arteriovenous malformations (ADAVMs) are rare vascular anomalies traditionally managed with surgery, which may lead to morbidity, recurrence, and functional impairment. Evidence regarding laser therapy\u2014historically considered contraindicated in arteriovenous malformations\u2014is extremely limited, and no large cohort has been reported to date.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To report the largest cohort of ADAVMs treated with laser therapy and to determine whether dual sequential pulsed dye (595\u2009nm) and Nd:YAG (1064\u2009nm) laser therapy is an effective and safe alternative to surgery for Sch\u00f6binger stage I ADAVMs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective case series (2010\u20132025) including 26 patients with ADAVMs was conducted. Sch\u00f6binger stage I lesions were treated using dual sequential 595\u2010nm pulsed dye and 1064\u2010nm Nd:YAG laser (Multiplex mode). Clinical characteristics, treatment parameters, outcomes, and satisfaction were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Laser therapy achieved complete lesion clearance after a mean of 1.5 sessions, with a median clinical improvement of 100% and no recurrences over a median follow\u2010up of 85.5 months. Three patients with previous surgical failure also achieved full resolution. No bleeding episodes, adverse effects, or procedural complications were observed. The most commonly used parameters included a 7\u2010mm spot size, 595\u2009nm PDL at 6\u20138\u2009J\/cm\u00b2 and 10\u2009ms, followed by 1064\u2009nm Nd:YAG at 70\u2013100\u2009J\/cm\u00b2 and 15\u2009ms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Relevance<\/jats:title>\n                    <jats:p>Dual sequential PDL\/Nd:YAG laser therapy appears to be a highly effective, safe, and minimally invasive alternative to surgery for Sch\u00f6binger stage I ADAVMs, supporting its potential role as a first\u2010line therapeutic option.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lsm.70121","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T04:46:03Z","timestamp":1773117963000},"page":"388-394","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dual PDL 595\u2009nm\u2013Nd:YAG 1064\u2009nm Laser as an Alternative to Surgery in Acquired Digital Arteriovenous Malformations: A 26\u2010Patient Retrospective Cohort"],"prefix":"10.1002","volume":"58","author":[{"given":"Blanca","family":"Santos\u2010Latasa","sequence":"first","affiliation":[{"name":"Department of Dermatology, Laser Unit University Hospital Ram\u00f3n y Cajal Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3940-1165","authenticated-orcid":false,"given":"Jaime Company","family":"Quiroga","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Laser Unit University Hospital Ram\u00f3n y Cajal Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Pablo Boixeda de","family":"Miquel","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Laser Unit University Hospital Ram\u00f3n y Cajal Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,9]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2019.11.130"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2022.08.054"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1604299"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hcl.2016.08.010"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1604299"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adengl.2013.09.005"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2000.03348.x"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.04990.x"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.14913"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.7860\/JCDR\/2019\/40669.12985"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.04.031"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2011.1513"}],"container-title":["Lasers in Surgery and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.70121","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lsm.70121","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lsm.70121","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T05:29:56Z","timestamp":1781587796000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lsm.70121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,9]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/lsm.70121"],"URL":"https:\/\/doi.org\/10.1002\/lsm.70121","archive":["Portico"],"relation":{},"ISSN":["0196-8092","1096-9101"],"issn-type":[{"value":"0196-8092","type":"print"},{"value":"1096-9101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,9]]},"assertion":[{"value":"2025-12-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}