{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:24:19Z","timestamp":1786119859523,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Lasers Surg Med"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This manuscript reviews studies on the use of pulsed dye laser (PDL) and intense pulsed light (IPL) for the treatment of cutaneous rosacea, with a focus on their emerging role in managing ocular rosacea.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A literature search was conducted using the PubMed database with the terms \u201crosacea and intense pulsed light\u201d, \u201cocular rosacea and intense pulsed light\u201d, \u201crosacea and pulsed dye laser\u201d, and \u201cocular rosacea and pulsed dye laser.\u201d Of the 81 initially identified articles, studies not in English and those published before 1999 were excluded to ensure relevance to modern laser technologies. Additionally, review articles and case reports with three or fewer patients were excluded due to limited generalizability and statistical robustness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>After applying exclusion criteria, 20 articles remained. Studies consistently demonstrated significant improvement in erythema and telangiectasia following multiple sessions of PDL or IPL, with minimal differences between the two modalities. However, one study reported that IPL treatment was faster to administer. While IPL has been widely studied in ophthalmology for treating dry eye syndrome and meibomian gland dysfunction, it has also been shown to effectively alleviate ocular rosacea symptoms, reducing lid margin telangiectasia and improving meibum expressibility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PDL and IPL have demonstrated efficacy and safety in managing cutaneous rosacea, and IPL has also proven beneficial for ocular rosacea. These findings support the expanding role of laser and light\u2010based therapies as effective treatment options for patients suffering from rosacea\u2010related symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lsm.70185","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T19:18:46Z","timestamp":1786043926000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pulsed Dye Laser and Intense Pulsed Light Therapy for Cutaneous and Ocular Rosacea: A Systematic Review"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3801-0744","authenticated-orcid":false,"given":"Olamide Sonuga","family":"Finney","sequence":"first","affiliation":[{"name":"Department of Dermatology, School of Medicine University of California, Irvine Irvine California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Soliman","sequence":"additional","affiliation":[{"name":"Department of Medicine Loma Linda University School of Medicine Loma Linda California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moonjung","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology &amp; Visual Sciences, Gavin Herbert Eye Institute School of Medicine, University of California, Irvine Irvine California USA"},{"name":"Department of Ophthalmology National Health Insurance Service Ilsan Hospital Goyang Gyeonggi South\u00a0Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5883-5188","authenticated-orcid":false,"given":"Christopher B.","family":"Zachary","sequence":"additional","affiliation":[{"name":"Department of Dermatology, School of Medicine University of California, Irvine Irvine California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia L.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology &amp; Visual Sciences, Gavin Herbert Eye Institute School of Medicine, University of California, Irvine Irvine California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5988-2197","authenticated-orcid":false,"given":"Kristen M.","family":"Kelly","sequence":"additional","affiliation":[{"name":"Department of Dermatology, School of Medicine University of California, Irvine Irvine California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1542-0124(12)70121-0"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2018.06.002"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/19381980.2017.1361574"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-198910000-00007"},{"key":"e_1_2_6_6_1","volume-title":"Intense Pulsed Light (IPL) Therapy","author":"Gade A.","year":"2024"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-002-8263-8"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2004.02.011"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20621"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.12284"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22819"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/14628839950516922"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2003.29141.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2005.31204"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08702.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/14764172.2011.613480"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.3109\/14764172.2014.957218"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2014.26.4.491"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2020.8617"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.36849\/JDD.4920"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2009.01156.x"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/14764172.2018.1528371"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/14764172.2020.1717540"},{"key":"e_1_2_6_24_1","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1684\/ejd.2022.4301","article-title":"Prospective Evaluation of Intense Pulsed Light Treatment for Meibomian Gland Dysfunction and Blepharitis Due to Ocular Rosacea","volume":"32","author":"Verg\u00e9s C. 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