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The ROS generation assay resulted in a quantum yield of 0.19. Cell viability assays showed viability below 35% in 2D models, with confirmation in 3D models. In vitro release studies indicated a modified profile following encapsulation, and in vivo studies using acute toxicity models in\n                      <jats:italic>A. salina<\/jats:italic>\n                      suggested that the formulation is non\u2010toxic.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The results demonstrate that the nanostructured systems show promising performance, reinforcing the potential of stimulus\u2010responsive therapies in the treatment of BC.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lsm.70212","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:23:11Z","timestamp":1790259791000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development and Characterization of Liposomes Containing a Zn(II) Porphyrin Derivative for the Application of Photodynamic Therapy in the Treatment of Breast Cancer"],"prefix":"10.1002","author":[{"given":"Kammila Martins Nicolau","family":"Costa","sequence":"first","affiliation":[{"name":"Postgraduate Program in Development and Technological Innovation in Medicines Federal University of Para\u00edba  Jo\u00e3o Pessoa, Para\u00edba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2330-5494","authenticated-orcid":false,"given":"Jos\u00e9 Ferreira","family":"Sarmento\u2010Neto","sequence":"additional","affiliation":[{"name":"Department of Chemistry Federal University of Para\u00edba  Jo\u00e3o Pessoa, Para\u00edba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3818-029X","authenticated-orcid":false,"given":"J\u00falio Santos","family":"Rebou\u00e7as","sequence":"additional","affiliation":[{"name":"Department of Chemistry Federal University of 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