{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T00:31:21Z","timestamp":1790987481524,"version":"4.1.0"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":3864,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2005,2]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>\n                                 <jats:bold>We studied the impact of multiple bile duct anastomosis on the development of biliary complications after liver transplantation in children. A total of 101 patients received a primary liver transplant and were divided into 2 groups: those with a single bile duct (n = 77) and those with multiple bile ducts (n = 24). Mean follow-up was 39.8 \u00b1 20.8 months. A total of 27 patients presented with biliary complications (26.7%), 18 patients (18.7%) presented with early complications (12 leaks and 6 strictures), and 9 patients (8.9%) had late strictures. Hepatic artery thrombosis (HAT) and multiple bile ducts were significant risk factors for the development of biliary complications, and the presence of multiple bile ducts was an independent risk factor. Patients with multiple bile ducts had a significantly greater incidence of total biliary complications compared to those with single ducts. Patients with multiple ducts had a higher incidence of leaks when compared to those in the single duct group, but the incidence of strictures, both early and late, was similar in both groups. One-year patient and graft survivals were not statistically different in the 2 groups. In conclusion, the presence of more than one bile duct in the graft is an independent risk factor for the development of biliary complications after pediatric liver transplantation. (Liver Transpl 2005;11:161\u2013166.)<\/jats:bold>\n                              <\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/lt.20288","type":"journal-article","created":{"date-parts":[[2005,1,21]],"date-time":"2005-01-21T17:16:37Z","timestamp":1106327797000},"page":"161-166","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":53,"title":["Presence of multiple bile ducts in the liver graft increases the incidence of biliary complications in pediatric liver transplantation"],"prefix":"10.1097","volume":"11","author":[{"given":"Paolo R.O.","family":"Salvalaggio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter F.","family":"Whitington","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estella M.","family":"Alonso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo A.","family":"Superina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"Suppl 1","key":"R1-7-20250326","doi-asserted-by":"crossref","first-page":"S44","DOI":"10.1097\/00005176-200207001-00011","article-title":"Liver transplantation in children.","volume":"35","author":"Whitington","year":"2002","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"R2-7-20250326","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/0022-3468(94)90321-2","article-title":"The spectrum of bile duct complications in pediatric liver transplantation.","volume":"29","author":"Peclet","year":"1994","journal-title":"J Pediatr Surg"},{"key":"R3-7-20250326","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1007\/s00268-001-0114-4","article-title":"Biliary anastomotic complications in 400 living related liver transplantations.","volume":"25","author":"Egawa","year":"2001","journal-title":"World J Surg"},{"key":"R4-7-20250326","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/j.1432-2277.2000.tb01006.x","article-title":"Hepatic grafts from live donors: donor morbidity for 470 cases of live donation.","volume":"13","author":"Fujita","year":"2000","journal-title":"Transpl Int"},{"key":"R6-7-20250326","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1016\/S0041-1345(03)00463-9","article-title":"Biliary complications after pediatric liver transplantation revisited.","volume":"35","author":"Heffron","year":"2003","journal-title":"Transplant Proc"},{"key":"R7-7-20250326","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1016\/0022-3468(93)90139-C","article-title":"Biliary tract complications in pediatric orthotopic liver transplantation.","volume":"28","author":"Lallier","year":"1993","journal-title":"J Pediatr Surg"},{"key":"R8-7-20250326","doi-asserted-by":"crossref","first-page":"2738","DOI":"10.1016\/S0041-1345(01)02174-1","article-title":"Longterm efficacy of endoscopic stenting in patients with stricture of the biliary anastomosis after orthotopic liver transplantation.","volume":"33","author":"Chahin","year":"2001","journal-title":"Transplant Proc"},{"key":"R9-7-20250326","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1007\/s00268-001-0113-5","article-title":"Complications of biliary tract in liver transplantation.","volume":"25","author":"Testa","year":"2001","journal-title":"World J Surg"},{"key":"R10-7-20250326","first-page":"367","article-title":"Reducedsized orthotopic liver graft in hepatic transplantation in children.","volume":"95","author":"Bismuth","year":"1984","journal-title":"Surgery"},{"key":"R13-7-20250326","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1097\/00007890-199908270-00017","article-title":"Analysis of survival and morbidity after pediatric liver transplantation with fullsize and technicalvariant grafts.","volume":"68","author":"Sieders","year":"1999","journal-title":"Transplantation"},{"key":"R14-7-20250326","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1097\/01.TP.0000061940.96949.A1","article-title":"Splitliver transplantation eliminates the need for livingdonor liver transplantation in children with endstage cholestatic liver disease.","volume":"75","author":"Gridelli","year":"2003","journal-title":"Transplantation"},{"key":"R15-7-20250326","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/S0022-3476(99)70450-6","article-title":"Pediatric liver transplantation with cadaveric or living related donors: comparative results in 90 elective recipients of primary grafts.","volume":"134","author":"Reding","year":"1999","journal-title":"J Pediatr"},{"key":"R16-7-20250326","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0041-1345(96)00160-1","article-title":"2nd, Alonso EM, Piper JB, Newell KA, Bruce DS, Woodle ES, et al. 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