{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T11:20:43Z","timestamp":1776424843141,"version":"3.51.2"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":3895,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>\n                                 <jats:bold>Nonalcoholic fatty liver disease (NAFLD) has been reported in adults with hypothalamic or pituitary dysfunction, and some have progressed to end stage liver disease requiring transplantation. We report a teenager who intially presented with hypoxia due to intrapulmonary shunting, found to have NAFLD and cirrhosis associated with a hypothalamic tumor and panhypopituitarism. The NAFLD recurred very quickly after a successful liver transplant. Hepatopulmonary syndrome may be more common in cirrhosis associated with pituitary dysfunction than in other types of cirrhosis.<\/jats:bold>\n                              <\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/lt.20332","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:16:14Z","timestamp":1104538574000},"page":"108-110","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":39,"title":["Rapid Recurrence of Nonalcoholic Fatty Liver Disease After Transplantation in a Child With Hypopituitarism and Hepatopulmonary Syndrome"],"prefix":"10.1097","volume":"11","author":[{"given":"Maureen M.","family":"Jonas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura E.","family":"Krawczuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heung Bae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig","family":"Lillehei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Perez-Atayde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-19-20250326","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1210\/jc.2002-021180","article-title":"Risk factors for the development of obesity in children surviving brain tumors.","volume":"88","author":"Lustig","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"R2-19-20250326","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/j.1469-8749.2004.tb00476.x","article-title":"Outcome of craniopharyngioma in children: long-term complications and quality of life.","volume":"46","author":"Poretti","year":"2004","journal-title":"Dev Med Child 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years old boy (Abstract).","volume":"39","author":"Jankowska","year":"2004","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"R7-19-20250326","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1136\/adc.76.6.537","article-title":"Effect of growth hormone on fatty liver in panhypopituitarism.","volume":"76","author":"Takano","year":"1997","journal-title":"Arch Dis Child"},{"key":"R8-19-20250326","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/S0022-3476(75)80900-0","article-title":"Liver dysfunction and histologic abnormalities in neonatal hypopituitarism.","volume":"87","author":"Herman","year":"1975","journal-title":"J Pediatr"},{"key":"R9-19-20250326","first-page":"787","article-title":"Neonatal cholestasis and hypopituitarism.","volume":"59","author":"Kaufman","year":"1984","journal-title":"Acta Paediatr Scand"},{"key":"R10-19-20250326","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/0002-9149(92)91200-N","article-title":"Frequency and significance of intrapulmonary right-to-left shunting in end-stage hepatic disease.","volume":"70","author":"Hopkins","year":"1992","journal-title":"Am J Cardiol"}],"container-title":["Liver 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