{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T16:52:24Z","timestamp":1788540744142,"version":"build-2803163510"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Supplement 2","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":3226,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2006,11]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>\n                                 <jats:bold>Key Concepts:<\/jats:bold>\n                              <\/jats:p>\n            <jats:p>\n                                 <jats:bold>1. Medical therapy alone is rarely sufficient for long-term management of patients with hepatic vein thrombosis.<\/jats:bold>\n                              <\/jats:p>\n            <jats:p>\n                                 <jats:bold>2. Enthusiasm for intravascular stents (transjugular intrahepatic portosystemic shunt [TIPS] or vena caval stents) for the management of Budd-Chiari syndrome must be tempered by the limited interval of expected utility, the likelihood of stent occlusion\/revisions, and the potential complications that stent migration would impose upon a subsequent liver transplant.<\/jats:bold>\n                              <\/jats:p>\n            <jats:p>\n                                 <jats:bold>3. Both decompressive shunts and liver transplantation provide excellent long-term survival for patients with the Budd-Chiari syndrome. The determination of which surgical procedure is most appropriate is aided by assessment of the etiology of hepatic vein thrombosis, hepatic reserve, liver histology, and splanchnic venous anatomy.<\/jats:bold>\n                              <\/jats:p>\n            <jats:p>\n                                 <jats:bold>4. Progressive hepatic damage may develop in patients with Budd-Chiari syndrome who have patent surgical shunts or TIPS. Lifelong follow-up and tracking of hepatic function are indicated. Some patients with shunts will require salvage with liver transplantation.<\/jats:bold>\n                              <\/jats:p>\n            <jats:p>\n                                 <jats:bold>5. Long-term anticoagulation should be considered after transplantation, even in patients who do not have an identifiable coagulation disorder. Liver Transpl 12:S23\u2013S28, 2006. \u00a9 2006 AASLD.<\/jats:bold>\n                              <\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/lt.20941","type":"journal-article","created":{"date-parts":[[2006,10,18]],"date-time":"2006-10-18T21:16:32Z","timestamp":1161206192000},"page":"S23-S28","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":59,"title":["Management of Budd-Chiari syndrome"],"prefix":"10.1097","volume":"12","author":[{"given":"Andrew S.","family":"Klein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-7-20250124","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/00000658-199008000-00005","article-title":"Current management of the BuddChiari syndrome.","volume":"212","author":"Klein","year":"1990","journal-title":"Ann 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